Cochrane · systematic review · CD009832

Zinc supplementation for tinnitus

Person, OC, Puga, MES, da Silva, EMK, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

ENTAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
2
No studies
5
Included studies
NR
No studies 5 · 71.4%Ungraded 0 · 0%Very low 2 · 28.6%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Comparison

Population: adults over 18 years with tinnitus
7 questions
OutcomeEffectEvidenceStatus / GRADE
Improvement in tinnitus severity and disability, measured by a validated tinnitus‐specific questionnaire (THQ) Proportion of patients improved 4 months
no estimate extracted1 study · 187 participantsVery low
Downgraded: publication bias
Adverse effects of treatment
no estimate extractedNRNo studies
Quality of life
no estimate extractedNRNo studies
Socioeconomic impact associated with work
no estimate extractedNRNo studies
Anxiety and depression disorders
no estimate extractedNRNo studies
Psychoacoustic parameters
no estimate extractedNRNo studies
Tinnitus loudness (dB)
MD 0.51 study · 41 participantsVery low
Downgraded: publication bias