Cochrane · systematic review · CD009760

Transcranial direct current stimulation (tDCS) for improving aphasia in adults with aphasia after stroke

Elsner, B, Kugler, J, Pohl, M, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library

Stroke3 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 33.3%Low 3 · 50%Moderate 1 · 16.7%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

tDCS plus speech and language therapy (SLT) versus sham tDCS plus SLT for improving aphasia for improving aphasia in patients with aphasia after stroke

Population: patients with improving aphasia in patients with aphasia after stroke
CD009760.PUB4 (current) · 6 questions
OutcomeEffectEvidenceStatus / GRADE
Functional communication post intervention Formal outcome measures of aphasia. Scale from: −infinity to +infinity
tDCS plus speech and language therapy (SLT) vs sham tDCS plus SLT
no estimate extracted3 studies · 112 participantsLow
Downgraded: imprecision, indirectness
Functional communication at
tDCS plus speech and language therapy (SLT) vs sham tDCS plus SLT
no estimate extracted2 studies · 80 participantsVery low
Downgraded: imprecision, indirectness
Language impairment: accuracy of naming nouns post intervention Accuracy in naming nouns. Scale from: −infinity to +infinity
tDCS plus speech and language therapy (SLT) vs sham tDCS plus SLT
no estimate extracted11 studies · 298 participantsModerate
Downgraded: imprecision
Language impairment: accuracy of naming nouns at
tDCS plus speech and language therapy (SLT) vs sham tDCS plus SLT
no estimate extracted2 studies · 80 participantsLow
Downgraded: imprecision
Language impairment: accuracy of naming verbs post intervention Accuracy in verb naming. Scale from: −infinity to +infinity
tDCS plus speech and language therapy (SLT) vs sham tDCS plus SLT
no estimate extracted3 studies · 21 participantsVery low
Downgraded: imprecision, indirectness
tDCS plus speech and language therapy (SLT) versus sham tDCS plus SLT for improving aphasia: dropouts post intervention Numbers of dropouts and adverse events
tDCS plus speech and language therapy (SLT) vs sham tDCS plus SLT
no estimate extracted15 studies · 345 participantsLow
Downgraded: imprecision, indirectness

tDCS plus speech and language therapy (SLT) versus sham tDCS plus SLT for improving aphasia for improving aphasia and cognition in patients with aphasia after stroke

Population: patients with improving aphasia and cognition in patients with aphasia after stroke
CD009760.PUB3 · 2 questions
OutcomeEffectEvidenceStatus / GRADE
Language impairment: accuracy of naming until end of intervention phase ‐ Accuracy of naming until end of intervention phase (change scores) Number of correct responses in a picture naming task
tDCS plus speech and language therapy (SLT) vs sham tDCS plus SLT
no estimate extracted6 studies · 66 participantsLow
Downgraded: risk of bias, imprecision
tDCS plus speech and language therapy (SLT) versus sham tDCS plus SLT for improving aphasia: dropouts Dropouts and adverse events
tDCS plus speech and language therapy (SLT) vs sham tDCS plus SLT
no estimate extracted8 studies · 115 participantsLow
Downgraded: risk of bias, imprecision

Comparison

Population: people (18+ years) with aphasia after stroke
CD009760.PUB2 · 1 question
OutcomeEffectEvidenceStatus / GRADE
Language impairment: accuracy of naming until end of intervention phase (relative change in standard units) Rule of thumb for interpretation: 0.2 represents a small effect, 0.5 a moderate effect, and 0.8 a large effect (Patrick 2011)
no estimate extracted5 studies · 54 participantsModerate