Cochrane · systematic review · CD009530
Bronchoscopy‐guided antimicrobial therapy for cystic fibrosis
Jain, K, Wainwright, CE, Smyth, AR · Cochrane Database of Systematic Reviews · 2024 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 5 · 71.4%Moderate 2 · 28.6%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Show all 4 versionsBAL‐directed therapy versus standard therapy for cystic fibrosis
Population: infants and children with pulmonary exacerbations in cystic fibrosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
FEV1: z score BAL‐directed therapy vs standard therapy | no estimate extracted | 2 studies · 186 participants | Low Downgraded: imprecision, indirectness |
FVC: absolute z score BAL‐directed therapy vs standard therapy | no estimate extracted | 1 study · 157 participants | Low Downgraded: imprecision, indirectness |
HRCT score BAL‐directed therapy vs standard therapy | no estimate extracted | 2 studies · 181 participants | Moderate Downgraded: imprecision, indirectness |
Nutritional parameters: z score for weight BAL‐directed therapy vs standard therapy | no estimate extracted | 2 studies · 186 participants | Low Downgraded: imprecision, indirectness |
Number of positive P aeruginosa isolates BAL‐directed therapy vs standard therapy | no estimate extracted | 1 study · 157 participants | Low Downgraded: imprecision, indirectness |
Hospitalisations: number per participant per year BAL‐directed therapy vs standard therapy | no estimate extracted | 1 study · 157 participants | Low Downgraded: imprecision, indirectness |
Cost of hospital care per participant (AUD) BAL‐directed therapy vs standard therapy | no estimate extracted | 1 study · 157 participants | Moderate Downgraded: imprecision, indirectness |