Cochrane · systematic review · CD009461
Hysteroscopy for treating subfertility associated with suspected major uterine cavity abnormalities
Bosteels, J, van Wessel, S, Weyers, S, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
3
No studies
5
Included studies
NR
No studies 5 · 62.5%Ungraded 0 · 0%Very low 2 · 25%Low 1 · 12.5%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyOperative hysteroscopy versus control in women with otherwise unexplained subfertility and suspected major uterine cavity abnormalities
Population: women with submucous fibroids and otherwise unexplained subfertility
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Live birth Operative hysteroscopy vs control | no estimate extracted | NR | No studies |
Adverse events: hysteroscopy complications Operative hysteroscopy vs control | no estimate extracted | NR | No studies |
Clinical pregnancya Ultrasound 12 months Operative hysteroscopy vs control | OR 2.44 [0.97, 6.17] | 1 study · 94 participants | Very low Downgraded: risk of bias, imprecision |
Adverse events: miscarriaged Ultrasound 12 months Operative hysteroscopy vs control | OR 1.54 [0.47, 5] | 1 study · 94 participants | Very low Downgraded: risk of bias, imprecision |
Operative hysteroscopy versus control in women undergoing medically assisted reproduction with suspected major uterine cavity abnormalities
Population: subfertile women with endometrial polyps diagnosed by ultrasonography prior to treatment with gonadotropin and intrauterine insemination
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Live birth Operative hysteroscopy vs control | no estimate extracted | NR | No studies |
Adverse events: hysteroscopy complications Operative hysteroscopy vs control | no estimate extracted | NR | No studies |
Clinical pregnancya Ultrasound 4 intrauterine insemination cycles Operative hysteroscopy vs control | OR 4.41 [2.45, 7.96] | 1 study · 204 participants | Low Downgraded: risk of bias, imprecision |
Adverse events: miscarriage Operative hysteroscopy vs control | no estimate extracted | NR | No studies |
Operative hysteroscopy compared with control for unexplained subfertility associated with suspected major uterine cavity abnormalities
Population: women with submucous fibroids and otherwise unexplained subfertility
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Live birth Operative hysteroscopy vs control | no estimate extracted | NR | No studies |
Hysteroscopy complications Operative hysteroscopy vs control | no estimate extracted | NR | No studies |
Clinical pregnancy ultrasound1 12 months Operative hysteroscopy vs control | OR 2.44 [0.97, 6.17] | 1 study · 94 participants | Very low Downgraded: risk of bias, imprecision |
Miscarriage ultrasound5 12 months Operative hysteroscopy vs control | OR 0.58 [0.12, 2.8] | 1 study · 30 participants | Very low Downgraded: risk of bias, imprecision |
Operative hysteroscopy compared with control for suspected major uterine cavity abnormalities prior to medically assisted reproduction
Population: subfertile women with endometrial polyps diagnosed by ultrasonography prior to treatment with gonadotropin and intrauterine insemination
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Live birth Operative hysteroscopy vs control | no estimate extracted | NR | No studies |
Hysteroscopy complications Operative hysteroscopy vs control | no estimate extracted | NR | No studies |
Clinical pregnancy ultrasound1 4 IUI cycles Operative hysteroscopy vs control | OR 4.41 [2.45, 7.96] | 1 study · 204 participants | Moderate Downgraded: risk of bias |
Miscarriage Operative hysteroscopy vs control | no estimate extracted | NR | No studies |
Comparison
Population: women with submucous fibroids and otherwise unexplained subfertility
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Clinical pregnancy ultrasound1 12 months | OR 2.44 [0.97, 6.17] | 1 study · 94 participants | Very low Downgraded: risk of bias, imprecision |
Miscarriage ultrasound5 12 months | OR 1.54 [0.71, 5] | 1 study · 94 participants | Very low Downgraded: risk of bias, imprecision |
Comparison
Population: subfertile women with endometrial polyps diagnosed by ultrasonography prior to treatment with gonadotropin and intrauterine insemination
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Clinical pregnancy ultrasound1 4 IUI cycles | OR 4.41 [2.45, 7.96] | 1 study · 204 participants | High |