Cochrane · systematic review · CD008995
Antibiotics prior to or at the time of embryo transfer in ART
Ameratunga, D, Yazdani, A, Kroon, B · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 25%Low 3 · 75%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlySummary of findings table ‐ Antibiotics compared to control (no antibiotics) for embryo transfer (ET) in assisted reproductive technology (ART)
Population: embryo transfer (ET) in assisted reproductive technology (ART)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Live birth rate (LBR) Summary of findings table ‐ Antibiotics vs control (no antibiotics) | OR 0.48 [0.1, 2.23] | 1 study · 27 participants | Low Downgraded: risk of bias, imprecision, indirectness |
Clinical pregnancy rate (CPR) Summary of findings table ‐ Antibiotics vs control (no antibiotics) | OR 1.01 [0.67, 1.55] | 2 studies · 377 participants | Low Downgraded: risk of bias, imprecision, indirectness |
Genital tract colonization Summary of findings table ‐ Antibiotics vs control (no antibiotics) | OR 0.59 [0.37, 0.95] | 1 study · 284 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Miscarriage Summary of findings table ‐ Antibiotics vs control (no antibiotics) | OR 4.04 [0.15, 108.57] | 1 study · 27 participants | Low Downgraded: risk of bias, imprecision, indirectness |
Comparison
Population: Patients undergoing ART cycles
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Clinical Pregnancy | OR 1.02 [0.66, 1.58] | 1 study · 350 participants | High |
Genital Tract Colonisation | OR 0.59 [0.37, 0.95] | 1 study · 284 participants | Moderate |