Cochrane · systematic review · CD008807

Pressure‐controlled versus volume‐controlled ventilation for acute respiratory failure due to acute lung injury (ALI) or acute respiratory distress syndrome (ARDS)

Chacko, B, Peter, JV, Tharyan, P, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library

Emergency and Critical CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 3 · 42.9%Very low 0 · 0%Low 1 · 14.3%Moderate 3 · 42.9%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Pressure‐controlled ventilation vs volume‐controlled ventilation for acute respiratory failure due to acute lung injury (ALI) or acute respiratory distress syndrome (ARDS)

Population: patients with acute respiratory failure due to acute lung injury (ALI) or acute respiratory distress syndrome (ARDS)
7 questions
OutcomeEffectEvidenceStatus / GRADE
Mortality in hospital
Pressure‐controlled ventilation vs volume‐controlled ventilation
RR 0.83 [0.67, 1.02]3 studies · 1089 participantsModerate
Downgraded: risk of bias, imprecision
Mortality in ICU
Pressure‐controlled ventilation vs volume‐controlled ventilation
RR 0.84 [0.71, 0.99]2 studies · 1062 participantsModerate
Downgraded: risk of bias
Mortality on
Pressure‐controlled ventilation vs volume‐controlled ventilation
RR 0.88 [0.73, 1.06]1 study · 983 participantsModerate
Downgraded: risk of bias, imprecision
Duration of mechanical ventilation
Pressure‐controlled ventilation vs volume‐controlled ventilation
no estimate extracted1 study · 983 participantsUngraded
Barotrauma
Pressure‐controlled ventilation vs volume‐controlled ventilation
RR 1.24 [0.87, 1.77]2 studies · 1062 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Organ failure
Pressure‐controlled ventilation vs volume‐controlled ventilation
no estimate extracted1 study · 79 participantsUngraded
Quality of life
Pressure‐controlled ventilation vs volume‐controlled ventilation
no estimate extracted0 studies · 0 participantsUngraded