Cochrane · systematic review · CD008530
Antibiotic therapy for preventing infections in people with acute stroke
Vermeij, JD, Westendorp, WF, Dippel, DWJ, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
StrokeAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
5
No studies
1
Included studies
NR
No studies 1 · 14.3%Ungraded 1 · 14.3%Very low 0 · 0%Low 0 · 0%Moderate 1 · 14.3%High 4 · 57.1%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: patients with acute ischaemic or haemorrhagic stroke
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Case fatality at the end of | RR 1.03 [0.87, 1.21] | 8 studies · 4422 participants | High |
Poor functional outcome at the end of | RR 0.99 [0.89, 1.1] | 7 studies · 4332 participants | Moderate Downgraded: indirectness |
Number of infections at the end of | RR 0.71 [0.58, 0.88] | 7 studies · 4317 participants | High |
Number of UTIs at the end of | RR 0.4 [0.32, 0.51] | 6 studies · 4257 participants | High |
Number of pneumonias at the end of | RR 0.95 [0.8, 1.13] | 6 studies · 4257 participants | High |
Occurrence of elevated body temperature | no estimate extracted | 2 studies · 2 participants | Ungraded |
Rate of serious adverse events | no estimate extracted | NR | No studies |