Cochrane · systematic review · CD008496

Non‐drug therapies for the secondary prevention of lower limb muscle cramps

Hawke, F, Sadler, SG, Katzberg, HD, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

Neuromuscular2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
21
current version
GRADE rated
8
No studies
13
Included studies
NR
No studies 13 · 61.9%Ungraded 0 · 0%Very low 4 · 19%Low 2 · 9.5%Moderate 2 · 9.5%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

Calf and hamstring stretching compared to no intervention for lower limb muscle cramps in older adults

Population: older adults with lower limb muscle cramps
CD008496.PUB3 (current) · 7 questions
OutcomeEffectEvidenceStatus / GRADE
Change in cramp frequency (cramps per night) (after 6 weeks)
Calf and hamstring stretching vs no intervention
no estimate extracted1 study · 80 participantsVery low
Downgraded: risk of bias, imprecision
Adverse events
Calf and hamstring stretching vs no intervention
no estimate extracted1 study · 80 participantsModerate
Downgraded: imprecision
Change in cramp severity (0 to 10 VAS; higher = worse pain) (after 6 weeks)
Calf and hamstring stretching vs no intervention
no estimate extracted1 study · 80 participantsLow
Downgraded: risk of bias
Proportion of participants experiencing cramps
Calf and hamstring stretching vs no intervention
no estimate extractedNRNo studies
Health‐related quality of life
Calf and hamstring stretching vs no intervention
no estimate extractedNRNo studies
Quality of sleep
Calf and hamstring stretching vs no intervention
no estimate extractedNRNo studies
Activities of daily living
Calf and hamstring stretching vs no intervention
no estimate extractedNRNo studies

Calf stretching compared to placebo stretching for lower limb muscle cramps in older adults

Population: older adults with lower limb muscle cramps
CD008496.PUB3 (current) · 7 questions
OutcomeEffectEvidenceStatus / GRADE
Cramp frequency (number of cramps in the last four weeks) (after 12 weeks)
Calf stretching vs placebo stretching
no estimate extracted1 study · 94 participantsLow
Downgraded: risk of bias
Adverse events
Calf stretching vs placebo stretching
no estimate extracted1 study · 94 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Cramp severity
Calf stretching vs placebo stretching
no estimate extractedNRNo studies
Proportion of participants experiencing cramps
Calf stretching vs placebo stretching
no estimate extractedNRNo studies
Health‐related quality of life
Calf stretching vs placebo stretching
no estimate extractedNRNo studies
Quality of sleep
Calf stretching vs placebo stretching
no estimate extractedNRNo studies
Activities of daily living
Calf stretching vs placebo stretching
no estimate extractedNRNo studies

Calf, quadriceps, and hamstring stretching compared to no stretching for leg cramps in 50‐ to 60‐year‐old women with metabolic syndrome

Population: 50‐ to 60‐year‐old women with metabolic syndrome
CD008496.PUB3 (current) · 7 questions
OutcomeEffectEvidenceStatus / GRADE
Cramp frequency (number of cramps in preceding week) (after 6 weeks)
Calf, quadriceps, and hamstring stretching vs no stretching
no estimate extracted1 study · 24 participantsVery low
Downgraded: risk of bias, imprecision
Adverse events
Calf, quadriceps, and hamstring stretching vs no stretching
no estimate extracted1 study · 24 participantsModerate
Downgraded: imprecision
Cramp severity (0 to 10 VAS; higher = more pain) (after 6 weeks)
Calf, quadriceps, and hamstring stretching vs no stretching
no estimate extracted1 study · 24 participantsVery low
Downgraded: risk of bias, indirectness
Proportion of participants experiencing cramps
Calf, quadriceps, and hamstring stretching vs no stretching
no estimate extractedNRNo studies
Health‐related quality of life
Calf, quadriceps, and hamstring stretching vs no stretching
no estimate extractedNRNo studies
Quality of sleep
Calf, quadriceps, and hamstring stretching vs no stretching
no estimate extractedNRNo studies
Activities of daily living
Calf, quadriceps, and hamstring stretching vs no stretching
no estimate extractedNRNo studies

Calf muscle stretching versus placebo stretching for lower limb muscle cramps

Population: patients with lower limb muscle cramps
CD008496.PUB2 · 4 questions
OutcomeEffectEvidenceStatus / GRADE
Lower limb cramp frequency Participant recall
Calf muscle stretching vs placebo stretching
no estimate extracted1 study · 94 participantsVery low
Downgraded: imprecision
Lower limb cramp pain severity Pain scale
Calf muscle stretching vs placebo stretching
no estimate extracted0 studies · 0 participantsUngraded
Lower limb cramp duration
Calf muscle stretching vs placebo stretching
no estimate extracted0 studies · 0 participantsUngraded
Adverse effects of interventions for lower limb muscle cramp
Calf muscle stretching vs placebo stretching
no estimate extracted1 study · 94 participantsVery low
Downgraded: imprecision