Cochrane · systematic review · CD008493
Preoperative statin therapy for patients undergoing cardiac surgery
Kuhn Elmar W, Slottosch Ingo, Wahlers Thorsten, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 14.3%Moderate 6 · 85.7%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyStatin therapy for patients undergoing cardiac surgery
Population: patients undergoing cardiac surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality | OR 1.8 [0.38, 8.54] | 2 studies · 300 participants | Moderate Downgraded: imprecision |
Myocardial infarction ECG/cardiac enzymes | OR 0.48 [0.21, 1.13] | 7 studies · 901 participants | Low |
Atrial fibrillation ECG | OR 0.54 [0.43, 0.67] | 12 studies · 1765 participants | Moderate Downgraded: publication bias |
Stroke | OR 0.7 [0.14, 3.63] | 2 studies · 264 participants | Moderate |
Renal failure Serum creatinine/urea | OR 0.57 [0.3, 1.1] | 5 studies · 467 participants | Moderate |
Length of stay on ICU | no estimate extracted | 9 studies · 721 participants | Moderate |
Length of stay in hospital | no estimate extracted | 11 studies · 1137 participants | Moderate |
Statin therapy for patients undergoing cardiac surgery
Population: patients with patients undergoing cardiac surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality | OR 0.98 [0.14, 7.1] | 1 study · 200 participants | High |
Myocardial infarction ECG/cardiac enzymes | OR 0.52 [0.2, 1.3] | 9 studies · 897 participants | High |
Atrial fibrillation ECG | OR 0.4 [0.29, 0.55] | 8 studies · 841 participants | High |
Stroke | OR 0.7 [0.14, 3.63] | 5 studies · 374 participants | High |
Renal failure serum creatinin/urea | OR 0.41 [0.15, 1.12] | 4 studies · 367 participants | High |
Length of stay on ICU | no estimate extracted | 7 studies · 521 participants | High |
Length of stay in hospital | no estimate extracted | 8 studies · 877 participants | High |