Cochrane · intervention · CD008464
Interventions for the treatment of keratocystic odontogenic tumours
Sharif, FNJ, Oliver, R, Sweet, C, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
Full textEvery question was extracted from the full review (methods and results), not only its Summary of Findings table.
Questions
1
current version
GRADE rated
0
No studies
1
Included studies
0
as reported
No studies 1 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Adults over the age of 18 with a validated diagnosis of solitary keratocystic odontogenic tumours (KCOT) arising in the jaw bones of the maxilla or mandible; patients with known Gorlin syndrome excluded; participants under 18 excluded (most paediatric cases thought linked to Gorlin syndrome / PTCH gene mutations) | No included studies |
| Intervention | Any intervention for KCOT (e.g. enucleation, marsupialisation), alone or with an adjunctive therapy (ostectomy, cryotherapy, or Carnoy's solution) | No included studies |
| Comparison | A different intervention (e.g. enucleation versus marsupialisation), or the same surgical intervention without the adjunctive therapy | No included studies |
| Outcomes | Primary: radiographic or clinical evidence of recurrence (validated); need for further surgery. Secondary: morbidity; surgical complications; quality of life (validated questionnaires); hospital bed days and associated cost implications. Adverse effects: any unexpected/adverse events documented if identified | No included studies |
| Study designs | Randomised controlled trials (RCTs) | No included studies |
| Timing | Not specified | No included studies |
Search date: 2015-03. Databases: The Cochrane Oral Health Group's Trials Register; The Cochrane Central Register of Controlled Trials (CENTRAL); MEDLINE via OVID; EMBASE via OVID; US National Institutes of Health Trials Register (ClinicalTrials.gov); WHO Clinical Trials Registry Platform
Questions and results
Current version onlyAny intervention for KCOT (e.g. enucleation), alone or combined with an adjunctive therapy (ostectomy, cryotherapy, or Carnoy's solution) vs A different intervention (e.g. enucleation versus marsupialisation), or the same surgical intervention without the adjunctive therapy
Population: Adults over the age of 18 with a validated diagnosis of solitary keratocystic odontogenic tumours (KCOT) arising in the jaw bones of the maxilla or mandible; patients with known Gorlin syndrome excluded; participants under 18 excluded (most paediatric cases thought linked to Gorlin syndrome / PTCH gene mutations)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Outcome NR | No randomised controlled trials that met the inclusion criteria were identified. In view of the fact that no studies were identified, no data were available for analysis. | 0 studies | No studies |
Any intervention for KCOT (e.g. enucleation), alone or combined with an adjunctive therapy (ostectomy, cryotherapy, or Carnoy's solution) vs A different intervention (e.g. enucleation versus marsupialisation), or the same surgical intervention without the adjunctive therapy
Population: Adults over the age of 18 with a validated diagnosis of solitary keratocystic odontogenic tumours (KCOT) arising in the jaw bones of the maxilla or mandible; patients with known Gorlin syndrome excluded; participants under 18 excluded (most paediatric cases thought linked to Gorlin syndrome / PTCH gene mutations)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Outcome NR | No randomised controlled trials that met the inclusion criteria were identified. In view of the fact that no studies were identified, no data were available for analysis. | 0 studies | No studies |
Any intervention for KCOT (e.g. enucleation), alone or combined with an adjunctive therapy (ostectomy, cryotherapy, or Carnoy's solution) vs A different intervention (e.g. enucleation versus marsupialisation), or the same surgical intervention without the adjunctive therapy
Population: Adults over the age of 18 with a validated diagnosis of solitary keratocystic odontogenic tumours (KCOT) arising in the jaw bones of the maxilla or mandible; patients with known Gorlin syndrome excluded
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Outcome NR | Objectives: To assess the available evidence comparing the effectiveness of surgical interventions and adjuncts for the treatment of keratocystic odontogenic tumours. (Protocol; no search conducted and no results… | NR | No studies |