Cochrane · systematic review · CD008313
Co‐bedding in neonatal nursery for promoting growth and neurodevelopment in stable preterm twins
Lai, NM, Foong, SC, Foong, WC, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 3 · 42.9%Low 3 · 42.9%Moderate 1 · 14.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyCo‐bedding versus separate care for promoting growth and neurodevelopment in stable preterm twins
Population: stable preterm twins with growth and neurodevelopment promoted
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Rate of weight gain (in grams/kg of baseline weight/d) ‐ average from study entry to week 3 Grams per kilogram per day Co‐bedding vs separate care | no estimate extracted | 1 study · 18 participants | Low Downgraded: risk of bias, imprecision |
Apnea, bradycardia, or desaturation Number of twins with episodes Co‐bedding vs separate care | RR 0.85 [0.18, 4.05] | 1 study · 124 participants | Low Downgraded: imprecision, indirectness |
Episodes in co‐regulated state (out of 20 observations) Episodes observed (out of a total of 20 observations) Scale from 0 to 20 Co‐bedding vs separate care | no estimate extracted | 1 study · 6 participants | Very low Downgraded: risk of bias, imprecision |
Infections ‐ suspected or proven infections (any) Clinical and microbiological methods Co‐bedding vs separate care | RR 0.84 [0.3, 2.31] | 3 studies · 65 participants | Very low Downgraded: risk of bias, imprecision |
Length of hospital stay (days) Co‐bedding vs separate care | no estimate extracted | 1 study · 6 participants | Very low Downgraded: risk of bias, imprecision |
Parental satisfaction Parental satisfaction survey Scale from 0 to 55 Co‐bedding vs separate care | no estimate extracted | 1 study · 18 participants | Moderate Downgraded: risk of bias |
Neurobehavior: infant pain score following painful procedure ‐ at 30 seconds post heel lance Premature Infant Pain Profile (PIPP) Scale from 0 to 21 Co‐bedding vs separate care | no estimate extracted | 2 studies · 224 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Co‐bedding compared to separate care for promoting growth and neurodevelopment in stable preterm twins
Population: patients with promoting growth and neurodevelopment in stable preterm twins
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Rate of weight gain (in gram/kg of baseline weight/day) ‐ Average from study entry to week three Grams per kilogram per day Co‐bedding vs separate care | no estimate extracted | 1 study · 18 participants | Low Downgraded: risk of bias |
Apnoea, bradycardia or desaturation Number of twins with the episodes Co‐bedding vs separate care | RR 0.85 [0.18, 4.05] | 1 study · 124 participants | Low |
Episodes in coregulated state (out of 20 observations) Episodes observed (out of a total of 20 observations). Scale from: 0 to 20. Co‐bedding vs separate care | no estimate extracted | 1 study · 6 participants | Very low Downgraded: risk of bias |
Neurobehaviour: infant pain score following painful procedure ‐ At 90 seconds post heel lance Premature Infant Pain Profile (PIPP). Scale from: 0 to 21. Co‐bedding vs separate care | no estimate extracted | 1 study · 124 participants | High |
Infections ‐ Suspected or proven infections (any) Clinical and microbiological methods Co‐bedding vs separate care | RR 0.84 [0.3, 2.31] | 3 studies · 65 participants | Low Downgraded: risk of bias |
Length of hospital stay (Days) Co‐bedding vs separate care | no estimate extracted | 1 study · 6 participants | Very low Downgraded: risk of bias |
Parental satisfaction Parental Satisfaction Survey. Scale from: 0 to 55 Co‐bedding vs separate care | no estimate extracted | 1 study · 18 participants | Moderate Downgraded: risk of bias |