Cochrane · systematic review · CD008123

Medical treatment for botulism

Chalk, CH, Benstead, TJ, Pound, JD, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library

Neuromuscular2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 20%Moderate 4 · 80%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 2 versions

Human‐derived botulinum immune globulin intravenous for infant botulism

Population: individuals with infant botulism
5 questions
OutcomeEffectEvidenceStatus / GRADE
In‐hospital death from any cause occurring within 4 weeks of randomization or the beginning of treatment
no estimate extracted1 study · 122 participantsModerate
Downgraded: risk of bias
Duration of hospitalization (in weeks)
no estimate extracted1 study · 122 participantsModerate
Downgraded: risk of bias
Duration of mechanical ventilation (in weeks)
no estimate extracted1 study · 59 participantsLow
Downgraded: risk of bias
Duration of tube or parenteral feeding (in weeks)
no estimate extracted1 study · 122 participantsModerate
Downgraded: risk of bias
Risk of adverse events (until time of hospital discharge)
RR 0.92 [0.72, 1.18]1 study · 129 participantsModerate
Downgraded: risk of bias