Cochrane · systematic review · CD007380
Psychostimulant drugs for cocaine dependence
Castells, X, Cunill, R, Pérez‐Mañá, C, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
Drugs and AlcoholAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 66.7%Low 0 · 0%Moderate 1 · 33.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Psychostimulants for cocaine dependence
Population: people with cocaine dependence
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Cocaine use assessed by the mean (SD) proportion of cocaine‐free urinalysis across the study per participant | no estimate extracted | 8 studies · 526 participants | Very low Downgraded: risk of bias, imprecision |
Sustained cocaine abstinence | RR 1.36 [1.05, 1.77] | 14 studies · 1549 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Number of participants who finished the study | RR 1 [0.93, 1.06] | 24 studies · 2205 participants | Moderate |