Cochrane · systematic review · CD007271

Early versus late tracheostomy for critically ill patients

Andriolo, BNG, Andriolo, RB, Saconato, H, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library

Emergency and Critical Care2 versionsAMSTAR 2: not assessed

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.

Questions

current version

GRADE rated

No studies

Included studies

No studies 0 · 0%Ungraded 0 · 0%Very low 3 · 50%Low 0 · 0%Moderate 2 · 33.3%High 1 · 16.7%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

Early vs late tracheostomy for critically ill patients

Population: critically ill patients

CD007271.PUB3 (current) · 6 questions

Outcome	Effect	Evidence	Status / GRADE
Mortality at longest Early vs late tracheostomy	RR 0.83 [0.7, 0.98]	7 studies · 1903 participants	Moderate Downgraded: risk of bias, inconsistency, publication bias
Ventilator‐free days during 1 to 28 days Early vs late tracheostomy	no estimate extracted	2 studies · 335 participants	Moderate Downgraded: risk of bias, inconsistency, publication bias
Days of MV during 1 to 60 days Early vs late tracheostomy	no estimate extracted	2 studies · 336 participants	Very low Downgraded: risk of bias, inconsistency, publication bias
Length of ICU stay Early vs late tracheostomy	no estimate extracted	2 studies · 336 participants	Very low Downgraded: risk of bias, inconsistency, publication bias
ICU discharge (at day 28 after randomization) Early vs late tracheostomy	RR 1.29 [1.08, 1.55]	2 studies · 538 participants	High
Pneumonia Early vs late tracheostomy	no estimate extracted	5 studies · 948 participants	Very low

Early tracheostomy compared to late tracheostomy for critically ill patients

Population: patients with critically ill patients

CD007271.PUB2 · 3 questions

Outcome	Effect	Evidence	Status / GRADE
Mortality at maximal Early tracheostomy vs late tracheostomy	no estimate extracted	3 studies · 599 participants	Low Downgraded: risk of bias, inconsistency, publication bias
Time spent on mechanical ventilation8 days Early tracheostomy vs late tracheostomy	no estimate extracted	1 study · 120 participants	Moderate Downgraded: risk of bias, publication bias
Pneumonia Early tracheostomy vs late tracheostomy	no estimate extracted	2 studies · 539 participants	Low Downgraded: risk of bias, inconsistency, publication bias