Cochrane · systematic review · CD007026
Cerebrolysin for acute ischaemic stroke
Ziganshina, LE, Abakumova, T, Nurkhametova, D, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
4
No studies
3
Included studies
NR
No studies 3 · 42.9%Ungraded 0 · 0%Very low 1 · 14.3%Low 1 · 14.3%Moderate 2 · 28.6%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Show all 5 versionsCerebrolysin or Cerebrolysin‐like agents compared to placebo for acute ischaemic stroke
Population: people with acute ischaemic stroke
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause death ( Cerebrolysin or Cerebrolysin‐like agents vs placebo | RR 0.96 [0.65, 1.41] | 6 studies · 1689 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |
Non‐death attrition Cerebrolysin or Cerebrolysin‐like agents vs placebo | RR 0.72 [0.38, 1.39] | 6 studies · 1689 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Total number of people with SAEs** Cerebrolysin or Cerebrolysin‐like agents vs placebo | RR 1.16 [0.81, 1.66] | 3 studies · 1335 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |
Total number of people with adverse events, Cerebrolysin or Cerebrolysin‐like agents vs placebo | RR 1.03 [0.92, 1.14] | 4 studies · 1607 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Death or dependence, Cerebrolysin or Cerebrolysin‐like agents vs placebo | no estimate extracted | NR | No studies |
Early death (within 2 weeks of stroke onset) Cerebrolysin or Cerebrolysin‐like agents vs placebo | no estimate extracted | NR | No studies |
Quality of life Cerebrolysin or Cerebrolysin‐like agents vs placebo | no estimate extracted | NR | No studies |