Cochrane · intervention · CD006963
Treatments for adults with prominent lower front teeth
Cochrane Database of Systematic Reviews · 2012 · Cochrane Library
Full textEvery question was extracted from the full review (methods and results), not only its Summary of Findings table.
Questions
7
current version
GRADE rated
0
No studies
1
Included studies
2
as reported
No studies 1 · 14.3%Ungraded 6 · 85.7%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Individuals 16 years of age or older at the time of treatment with an Angle Class III malocclusion (with or without lower/upper jaw surgery); participants with syndromes, clefts and traumatically-induced deformities excluded | Two RCTs with 83 participants. Ritzau 1989: 53 patients (41 females, 12 males), average age 23.4 years, combined orthodontic and surgical treatment for prognathism. Yoshioka 2008: 30 Japanese adults with a prognathic mandible (mean age 18 to 20 years). |
| Intervention | All types of orthodontic treatment without surgery, with dentoalveolar compensation; All types of orthodontic treatment with extraction, with dentoalveolar compensation and without surgery; All types of techniques of fixed orthodontic appliances with or without extraction and with or without surgery; Maxillary advancement alone; Maxillary advancement and mandibular setback; Mandibular setback with bilateral sagittal split osteotomy (BSSO); Mandibular setback with vertical subsigmoid osteotomy (VSSO); Subcondylar osteotomy; Segmental osteotomy; Vertical oblique osteotomy; Mandibular step osteotomy (MSO); Oblique sliding osteotomy; All types of fixation (rigid fixation with plates and/or screws, semi-rigid fixation with wires, intermaxillary fixation); Surgically-assisted rapid palatal expansion (SARPE); Maxillary transversal surgical expansion by transpalatal distractor and Le Fort I osteotomy; Maxillary surgical impaction; Others | Vertical ramus osteotomy with osteosynthesis (n=26); Intraoral vertical ramus osteotomy (n=15) |
| Comparison | No intervention; Another technique | Vertical ramus osteotomy without osteosynthesis (n=27); Sagittal split ramus osteotomy (n=15) |
| Outcomes | Correction of prominent lower front teeth measured by the relationship between upper and lower central incisors, canines and molars, plaster models and/or cephalometric data and clinical assessment (primary); Stability of correction measured 1 year after treatment; Changes in condyle position measured by tomography; Alteration of pharyngeal airway space dimensions; Alteration of signs and symptoms of respiratory disease (snoring, mouth breathing, nasal airway resistance); Reduction or treatment of obstructive sleep apnea syndrome (OSAS) or upper airway resistance syndrome (UARS); Morbidities, side effects or patients' self report; Patients' satisfaction measured by self report; Quality of life measured by validated scale | Changes in condyle position (n=53); Stability of correction (n=30) |
| Study designs | Randomized controlled trials (RCTs) or quasi-randomized controlled trials | Two parallel-group randomized controlled trials (Ritzau 1989; Yoshioka 2008), both at high overall risk of bias |
| Timing | Not specified | 1 year post-surgery (stability assessed 1 week to 1 year) |
Search date: 2012-03. Databases: Cochrane Oral Health Group Trials Register; Cochrane Central Register of Controlled Trials (CENTRAL); MEDLINE via OVID; EMBASE via OVID; LILACs; Biblioteca Brasileira de Odontologia (BBO); SciELO
Questions and results
Current version onlyVertical ramus osteotomy (VRO) with osteosynthesis vs Vertical ramus osteotomy (VRO) without osteosynthesis
Population: Adults (16 years of age or older) with an Angle Class III malocclusion (prominent lower front teeth); people with syndromes, clefts or traumatically-induced deformities excluded
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Changes in condyle position: fossa-condyle relations for posterior (1 year post-operative) 1 year post-surgery | MD -0.10 [-0.64, 0.44] | 1 study · 53 participants | Ungraded |
Changes in condyle position: fossa-condyle relations for anterior (1 year post-operative) 1 year post-surgery | MD 0.00 [-0.38, 0.38] | 1 study · 53 participants | Ungraded |
Intraoral vertical ramus osteotomy (IVRO) vs Sagittal split ramus osteotomy (SSRO)
Population: Adults (16 years of age or older) with an Angle Class III malocclusion (prominent lower front teeth); people with syndromes, clefts or traumatically-induced deformities excluded
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Stability of correction: vertical changes of pogonion (1 week to 1 year) 1 week to 1 year post-surgery | MD 0.41 [-0.15, 0.97] | 1 study · 30 participants | Ungraded |
Stability of correction: sagittal changes of B-point (1 week to 1 year) 1 week to 1 year post-surgery | MD -0.22 [-0.58, 0.14] | 1 study · 30 participants | Ungraded |
Stability of correction: sagittal changes of pogonion (1 week to 1 year) 1 week to 1 year post-surgery | MD -0.24 [-0.67, 0.19] | 1 study · 30 participants | Ungraded |
Stability of correction: vertical changes of B-point (1 week to 1 year) 1 week to 1 year post-surgery | MD 0.09 [-0.44, 0.62] | 1 study · 30 participants | Ungraded |
Any orthodontic and/or surgical treatment for Angle Class III malocclusion vs No intervention or another treatment technique
Population: Adults (16 years of age or older) with an Angle Class III malocclusion (prominent lower front teeth); people with syndromes, clefts or traumatically-induced deformities excluded
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Correction of prominent lower front teeth / effectiveness of treatment (planned primary outcome) | No included study measured the planned primary outcome. Discussion: 'The primary outcome proposed for this review was to evaluate the effectiveness of treatments for prognathism, but none of the studies conclusively… | NR | No studies |
Mandibular setback osteotomy (vertical ramus / subsigmoid osteotomy) with osteosynthesis vs The same mandibular setback osteotomy without osteosynthesis
Population: Adults (16 years of age or older) with an Angle Class III malocclusion (prominent lower front teeth); people with syndromes, clefts or traumatically-induced deformities excluded
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Outcome NR | Protocol only: planned comparison of a mandibular setback osteotomy with versus without osteosynthesis (a fixation-method comparison within the protocol's planned surgical interventions and 'all types of fixation'); no… | NR | No studies |
Mandibular setback with vertical subsigmoid / intraoral vertical ramus osteotomy (VSSO/IVRO) vs Mandibular setback with bilateral sagittal split osteotomy (BSSO/SSRO)
Population: Adults (16 years of age or older) with an Angle Class III malocclusion (prominent lower front teeth); people with syndromes, clefts or traumatically-induced deformities excluded
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Outcome NR | Protocol only: planned comparison of two mandibular setback osteotomy techniques (vertical subsigmoid / intraoral vertical ramus osteotomy versus bilateral sagittal split osteotomy), both listed among the protocol's… | NR | No studies |
Any orthodontic and/or surgical treatment for Angle Class III malocclusion vs No intervention or another treatment technique
Population: Adults (16 years of age or older) with an Angle Class III malocclusion (prominent lower front teeth); people with syndromes, clefts or traumatically-induced deformities excluded
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Correction of prominent lower front teeth / effectiveness of treatment (planned primary outcome) | Protocol only: planned primary outcome (correction of prominent lower front teeth, measured by the relationship between upper and lower central incisors, canines and molars, plaster models and/or cephalometric data and… | NR | No studies |