Cochrane · intervention · CD006963

Treatments for adults with prominent lower front teeth

Cochrane Database of Systematic Reviews · 2012 · Cochrane Library

Oral HealthOrthodontics2 versionsAMSTAR 2: not assessed
Full textEvery question was extracted from the full review (methods and results), not only its Summary of Findings table.
Questions
7
current version
GRADE rated
0
No studies
1
Included studies
2
as reported
No studies 1 · 14.3%Ungraded 6 · 85.7%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Review question

ElementPlanned (methods)Found (results)
PopulationIndividuals 16 years of age or older at the time of treatment with an Angle Class III malocclusion (with or without lower/upper jaw surgery); participants with syndromes, clefts and traumatically-induced deformities excludedTwo RCTs with 83 participants. Ritzau 1989: 53 patients (41 females, 12 males), average age 23.4 years, combined orthodontic and surgical treatment for prognathism. Yoshioka 2008: 30 Japanese adults with a prognathic mandible (mean age 18 to 20 years).
InterventionAll types of orthodontic treatment without surgery, with dentoalveolar compensation; All types of orthodontic treatment with extraction, with dentoalveolar compensation and without surgery; All types of techniques of fixed orthodontic appliances with or without extraction and with or without surgery; Maxillary advancement alone; Maxillary advancement and mandibular setback; Mandibular setback with bilateral sagittal split osteotomy (BSSO); Mandibular setback with vertical subsigmoid osteotomy (VSSO); Subcondylar osteotomy; Segmental osteotomy; Vertical oblique osteotomy; Mandibular step osteotomy (MSO); Oblique sliding osteotomy; All types of fixation (rigid fixation with plates and/or screws, semi-rigid fixation with wires, intermaxillary fixation); Surgically-assisted rapid palatal expansion (SARPE); Maxillary transversal surgical expansion by transpalatal distractor and Le Fort I osteotomy; Maxillary surgical impaction; OthersVertical ramus osteotomy with osteosynthesis (n=26); Intraoral vertical ramus osteotomy (n=15)
ComparisonNo intervention; Another techniqueVertical ramus osteotomy without osteosynthesis (n=27); Sagittal split ramus osteotomy (n=15)
OutcomesCorrection of prominent lower front teeth measured by the relationship between upper and lower central incisors, canines and molars, plaster models and/or cephalometric data and clinical assessment (primary); Stability of correction measured 1 year after treatment; Changes in condyle position measured by tomography; Alteration of pharyngeal airway space dimensions; Alteration of signs and symptoms of respiratory disease (snoring, mouth breathing, nasal airway resistance); Reduction or treatment of obstructive sleep apnea syndrome (OSAS) or upper airway resistance syndrome (UARS); Morbidities, side effects or patients' self report; Patients' satisfaction measured by self report; Quality of life measured by validated scaleChanges in condyle position (n=53); Stability of correction (n=30)
Study designsRandomized controlled trials (RCTs) or quasi-randomized controlled trialsTwo parallel-group randomized controlled trials (Ritzau 1989; Yoshioka 2008), both at high overall risk of bias
TimingNot specified1 year post-surgery (stability assessed 1 week to 1 year)

Search date: 2012-03. Databases: Cochrane Oral Health Group Trials Register; Cochrane Central Register of Controlled Trials (CENTRAL); MEDLINE via OVID; EMBASE via OVID; LILACs; Biblioteca Brasileira de Odontologia (BBO); SciELO

Questions and results

Current version only

Vertical ramus osteotomy (VRO) with osteosynthesis vs Vertical ramus osteotomy (VRO) without osteosynthesis

Population: Adults (16 years of age or older) with an Angle Class III malocclusion (prominent lower front teeth); people with syndromes, clefts or traumatically-induced deformities excluded
CD006963.PUB2 (current) · 2 questions
OutcomeEffectEvidenceStatus / GRADE
Changes in condyle position: fossa-condyle relations for posterior (1 year post-operative)
1 year post-surgery
MD -0.10 [-0.64, 0.44]1 study · 53 participantsUngraded
Changes in condyle position: fossa-condyle relations for anterior (1 year post-operative)
1 year post-surgery
MD 0.00 [-0.38, 0.38]1 study · 53 participantsUngraded

Intraoral vertical ramus osteotomy (IVRO) vs Sagittal split ramus osteotomy (SSRO)

Population: Adults (16 years of age or older) with an Angle Class III malocclusion (prominent lower front teeth); people with syndromes, clefts or traumatically-induced deformities excluded
CD006963.PUB2 (current) · 4 questions
OutcomeEffectEvidenceStatus / GRADE
Stability of correction: vertical changes of pogonion (1 week to 1 year)
1 week to 1 year post-surgery
MD 0.41 [-0.15, 0.97]1 study · 30 participantsUngraded
Stability of correction: sagittal changes of B-point (1 week to 1 year)
1 week to 1 year post-surgery
MD -0.22 [-0.58, 0.14]1 study · 30 participantsUngraded
Stability of correction: sagittal changes of pogonion (1 week to 1 year)
1 week to 1 year post-surgery
MD -0.24 [-0.67, 0.19]1 study · 30 participantsUngraded
Stability of correction: vertical changes of B-point (1 week to 1 year)
1 week to 1 year post-surgery
MD 0.09 [-0.44, 0.62]1 study · 30 participantsUngraded

Any orthodontic and/or surgical treatment for Angle Class III malocclusion vs No intervention or another treatment technique

Population: Adults (16 years of age or older) with an Angle Class III malocclusion (prominent lower front teeth); people with syndromes, clefts or traumatically-induced deformities excluded
CD006963.PUB2 (current) · 1 question
OutcomeEffectEvidenceStatus / GRADE
Correction of prominent lower front teeth / effectiveness of treatment (planned primary outcome)
No included study measured the planned primary outcome. Discussion: 'The primary outcome proposed for this review was to evaluate the effectiveness of treatments for prognathism, but none of the studies conclusively…NRNo studies

Mandibular setback osteotomy (vertical ramus / subsigmoid osteotomy) with osteosynthesis vs The same mandibular setback osteotomy without osteosynthesis

Population: Adults (16 years of age or older) with an Angle Class III malocclusion (prominent lower front teeth); people with syndromes, clefts or traumatically-induced deformities excluded
CD006963 · 1 question
OutcomeEffectEvidenceStatus / GRADE
Outcome NR
Protocol only: planned comparison of a mandibular setback osteotomy with versus without osteosynthesis (a fixation-method comparison within the protocol's planned surgical interventions and 'all types of fixation'); no…NRNo studies

Mandibular setback with vertical subsigmoid / intraoral vertical ramus osteotomy (VSSO/IVRO) vs Mandibular setback with bilateral sagittal split osteotomy (BSSO/SSRO)

Population: Adults (16 years of age or older) with an Angle Class III malocclusion (prominent lower front teeth); people with syndromes, clefts or traumatically-induced deformities excluded
CD006963 · 1 question
OutcomeEffectEvidenceStatus / GRADE
Outcome NR
Protocol only: planned comparison of two mandibular setback osteotomy techniques (vertical subsigmoid / intraoral vertical ramus osteotomy versus bilateral sagittal split osteotomy), both listed among the protocol's…NRNo studies

Any orthodontic and/or surgical treatment for Angle Class III malocclusion vs No intervention or another treatment technique

Population: Adults (16 years of age or older) with an Angle Class III malocclusion (prominent lower front teeth); people with syndromes, clefts or traumatically-induced deformities excluded
CD006963 · 1 question
OutcomeEffectEvidenceStatus / GRADE
Correction of prominent lower front teeth / effectiveness of treatment (planned primary outcome)
Protocol only: planned primary outcome (correction of prominent lower front teeth, measured by the relationship between upper and lower central incisors, canines and molars, plaster models and/or cephalometric data and…NRNo studies