Cochrane · systematic review · CD006904

Protocolized versus non‐protocolized weaning for reducing the duration of mechanical ventilation in critically ill adult patients

Blackwood, B, Burns, KEA, Cardwell, CR, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library

Emergency and Critical Care2 versionsAMSTAR 2: not assessed

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.

Questions

current version

GRADE rated

No studies

Included studies

No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 40%Moderate 3 · 60%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

Comparison

Population: mechanically ventilated adult patients

CD006904.PUB3 (current) · 5 questions

Outcome	Effect	Evidence	Status / GRADE
Total duration of mechanical ventilation (hours)	no estimate extracted	14 studies · 2205 participants	Moderate Downgraded: imprecision, inconsistency
Weaning duration (hours)	no estimate extracted	8 studies · 989 participants	Low Downgraded: imprecision, inconsistency
ICU length of stay (days)	no estimate extracted	9 studies · 1378 participants	Low Downgraded: imprecision, inconsistency
ICU mortality	no estimate extracted	6 studies · 651 participants	Moderate Downgraded: imprecision, inconsistency
Reintubation	no estimate extracted	11 studies · 1487 participants	Moderate Downgraded: imprecision, inconsistency

Comparison

Population: mechanically ventilated adult patients

CD006904.PUB2 · 5 questions

Outcome	Effect	Evidence	Status / GRADE
Total duration of mechanical ventilation (hours)	no estimate extracted	10 studies · 1873 participants	Low Downgraded: risk of bias, imprecision, inconsistency
Weaning duration (hours)	no estimate extracted	6 studies · 854 participants	Low Downgraded: risk of bias, imprecision, inconsistency
ICU length of stay (days)	no estimate extracted	8 studies · 1256 participants	Low Downgraded: risk of bias, imprecision, inconsistency
ICU mortality	no estimate extracted	4 studies · 508 participants	Low Downgraded: risk of bias, imprecision, inconsistency
Reintubation	no estimate extracted	8 studies · 1314 participants	Low Downgraded: risk of bias, imprecision, inconsistency