Cochrane · systematic review · CD006237
Interventions to improve return to work in depressed people
Nieuwenhuijsen, K, Verbeek, JH, Neumeyer-Gromen, A, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
15
current version
GRADE rated
15
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 6.7%Low 7 · 46.7%Moderate 6 · 40%High 1 · 6.7%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyWork‐directed plus clinical intervention compared to care as usual in depressed people, medium‐term follow‐up
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Sickness absence days Work‐directed plus clinical intervention vs care | no estimate extracted | 9 studies · 1292 participants | Moderate Downgraded: risk of bias |
On sick leave Work‐directed plus clinical intervention vs care | RR 1.08 [0.64, 1.83] | 2 studies · 1025 participants | High |
Depressive symptoms‐ Work‐directed plus clinical intervention vs care | no estimate extracted | 8 studies · 1091 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Work functioning Work‐directed plus clinical intervention vs care | no estimate extracted | 5 studies · 926 participants | Low Downgraded: risk of bias |
Work‐directed intervention compared to care as usual in depressed people, medium‐term follow‐up
Population: Depressed persons
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Sickness absence days, medium‐term Work‐directed intervention vs care | no estimate extracted | 2 studies · 130 participants | Low Downgraded: risk of bias, imprecision |
Off work, medium‐term Work‐directed intervention vs care | RR 0.93 [0.77, 1.11] | 1 study · 226 participants | Moderate Downgraded: risk of bias, imprecision |
Depressive symptoms, medium‐term Work‐directed intervention vs care | no estimate extracted | 4 studies · 390 participants | Moderate Downgraded: risk of bias, imprecision |
Work functioning, medium‐term Work‐directed intervention vs care | no estimate extracted | 1 study · 48 participants | Low Downgraded: risk of bias, imprecision |
Psychological intervention compared to care as usual in depressed people, medium‐term follow‐up
Population: Depressed persons
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Sickness absence days, medium‐term Psychological intervention vs care | no estimate extracted | 9 studies · 1649 participants | Low Downgraded: risk of bias |
Depressive symptoms, medium‐term Psychological intervention vs care | no estimate extracted | 8 studies · 1255 participants | Low Downgraded: risk of bias, imprecision, publication bias |
Work ability, medium‐term Psychological intervention vs care | no estimate extracted | 1 study · 58 participants | Very low Downgraded: risk of bias, imprecision, publication bias |
Improved care compared to care as usual in depressed people, medium‐term follow‐up
Population: Depressed persons
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Sickness absence days, medium‐term Improved care vs care | no estimate extracted | 7 studies · 1912 participants | Moderate Downgraded: risk of bias, imprecision |
Off work, medium‐term Improved care vs care | RR 0.97 [0.77, 1.22] | 1 study · 362 participants | Low Downgraded: risk of bias, imprecision |
Depressive symptoms, medium‐term Improved care vs care | no estimate extracted | 7 studies · 1808 participants | Moderate Downgraded: risk of bias, imprecision |
Work functioning, medium‐term Improved care vs care | no estimate extracted | 1 study · 604 participants | Moderate Downgraded: risk of bias, imprecision |
Work‐directed intervention plus clinical intervention compared to clinical intervention alone for depressive disorder
Population: Persons with depressive disorder
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Days of sickness absence Work‐directed intervention plus clinical intervention vs clinical intervention alone | no estimate extracted | 3 studies · 251 participants | Moderate |
Any psychological intervention versus no intervention or care as usual for depressive disorder
Population: Persons with depressive disorder
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Days of sickness absence Any psychological intervention vs no intervention or care | no estimate extracted | 3 studies · 326 participants | Moderate |
Psychological intervention combined with antidepressant medication versus no intervention or usual care for depressive disorder
Population: Persons with depressive disorders
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Days of sickness absence ‐ Enhanced primary care versus CAU Psychological intervention combined with antidepressant medication vs no intervention or usual care | no estimate extracted | 2 studies · 969 participants | Low Downgraded: risk of bias, imprecision |
Days of sickness absence ‐ Telephone outreach and care management program versus CAU Psychological intervention combined with antidepressant medication vs no intervention or usual care | no estimate extracted | 1 study · 604 participants | High |