Cochrane · systematic review · CD005289

Monitoring of stimulated cycles in assisted reproduction (IVF and ICSI)

Kwan, I, Bhattacharya, S, Woolner, A · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

Gynaecology and Fertility2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
4
No studies
1
Included studies
NR
No studies 1 · 20%Ungraded 0 · 0%Very low 0 · 0%Low 4 · 80%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

Monitoring ovarian stimulation by transvaginal ultrasound (TVUS) only compared to monitoring with TVUS plus serum estradiol for women undergoing ovarian stimulation with gonadotrophins in IVF and ICSI procedures

Population: Women undergoing ovarian stimulation with gonadotrophins in IVF and ICSI procedures
CD005289.PUB4 (current) · 5 questions
OutcomeEffectEvidenceStatus / GRADE
Live birth per woman
Monitoring ovarian stimulation by transvaginal ultrasound (TVUS) only vs monitoring with TVUS plus serum estradiol
no estimate extractedNRNo studies
Clinical pregnancy per woman
Monitoring ovarian stimulation by transvaginal ultrasound (TVUS) only vs monitoring with TVUS plus serum estradiol
OR 1.1 [0.79, 1.54]4 studies · 617 participantsLow
Downgraded: risk of bias, imprecision
Mean number of oocytes retrieved per woman
Monitoring ovarian stimulation by transvaginal ultrasound (TVUS) only vs monitoring with TVUS plus serum estradiol
no estimate extracted5 studies · 595 participantsLow
Downgraded: risk of bias
OHSS rate (mild, moderate or severe) per woman
Monitoring ovarian stimulation by transvaginal ultrasound (TVUS) only vs monitoring with TVUS plus serum estradiol
OR 1.03 [0.48, 2.2]6 studies · 781 participantsLow
Downgraded: risk of bias, imprecision
Cycle cancellation rate per woman
Monitoring ovarian stimulation by transvaginal ultrasound (TVUS) only vs monitoring with TVUS plus serum estradiol
OR 0.57 [0.07, 4.39]2 studies · 115 participantsLow
Downgraded: risk of bias, imprecision

Monitoring ovarian stimulation by transvaginal ultrasound (TVUS) only compared to monitoring with TVUS plus serum estradiol for women undergoing ovarian stimulation with gonadotrophins in IVF and ICSI procedures

Population: Women undergoing ovarian stimulation with gonadotrophins in IVF and ICSI procedures
CD005289.PUB3 · 5 questions
OutcomeEffectEvidenceStatus / GRADE
Live birth per woman
Monitoring ovarian stimulation by transvaginal ultrasound (TVUS) only vs monitoring with TVUS plus serum estradiol
no estimate extractedNRNo studies
Clinical pregnancy per woman
Monitoring ovarian stimulation by transvaginal ultrasound (TVUS) only vs monitoring with TVUS plus serum estradiol
OR 1.05 [0.79, 1.54]4 studies · 617 participantsLow
Downgraded: risk of bias
Mean number of oocytes retrieved per woman
Monitoring ovarian stimulation by transvaginal ultrasound (TVUS) only vs monitoring with TVUS plus serum estradiol
no estimate extracted5 studies · 595 participantsLow
Downgraded: risk of bias
Cycle cancellation rate per woman
Monitoring ovarian stimulation by transvaginal ultrasound (TVUS) only vs monitoring with TVUS plus serum estradiol
OR 0.57 [0.07, 4.39]2 studies · 115 participantsLow
Downgraded: risk of bias, imprecision
OHSS rate (mild, moderate or severe) per woman
Monitoring ovarian stimulation by transvaginal ultrasound (TVUS) only vs monitoring with TVUS plus serum estradiol
OR 1.03 [0.48, 2.2]6 studies · 781 participantsLow
Downgraded: risk of bias, imprecision