Cochrane · systematic review · CD005252

Avoidance of bottles during the establishment of breastfeeds in preterm infants

Allen, E, Rumbold, AR, Keir, A, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

Neonatal3 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 75%Moderate 1 · 25%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

Breastfeeding with supplemental feeds by other than bottle compared with breastfeeding with supplemental feeds by bottle (all trials) in preterm infants

Population: preterm infants
CD005252.PUB5 (current) · 4 questions
OutcomeEffectEvidenceStatus / GRADE
Full breastfeeding compared with not breastfeeding or partial breastfeeding
Breastfeeding with supplemental feeds by other than bottle vs breastfeeding with supplemental feeds by bottle (all trials)
RR 1.47 [1.19, 1.8]6 studies · 1074 participantsLow
Downgraded: risk of bias, inconsistency
Any breastfeeding (full and partial combined) compared with not breastfeeding
Breastfeeding with supplemental feeds by other than bottle vs breastfeeding with supplemental feeds by bottle (all trials)
RR 1.11 [1.06, 1.16]6 studies · 1138 participantsModerate
Downgraded: risk of bias
Length of hospital stay (days)
Breastfeeding with supplemental feeds by other than bottle vs breastfeeding with supplemental feeds by bottle (all trials)
no estimate extracted4 studies · 1004 participantsLow
Downgraded: risk of bias, inconsistency
Episodes of infection per infant
Breastfeeding with supplemental feeds by other than bottle vs breastfeeding with supplemental feeds by bottle (all trials)
RR 0.7 [0.35, 1.42]3 studies · 500 participantsLow
Downgraded: risk of bias, imprecision

Breast feeding with supplemental feeds by other than bottle compared with breast feeding with supplemental feeds by bottle (all trials) in preterm infants

Population: preterm infants
CD005252.PUB4 · 8 questions
OutcomeEffectEvidenceStatus / GRADE
Full breast feeding at discharge
Breast feeding with supplemental feeds by other than bottle vs breast feeding with supplemental feeds by bottle (all trials)
RR 1.47 [1.19, 1.8]6 studies · 1074 participantsLow
Downgraded: risk of bias
Full breast feeding at 3 months post discharge
Breast feeding with supplemental feeds by other than bottle vs breast feeding with supplemental feeds by bottle (all trials)
RR 1.56 [1.37, 1.78]4 studies · 986 participantsModerate
Downgraded: risk of bias
Full breast feeding at 6 months post discharge
Breast feeding with supplemental feeds by other than bottle vs breast feeding with supplemental feeds by bottle (all trials)
RR 1.64 [1.14, 2.36]3 studies · 887 participantsLow
Downgraded: risk of bias
Any breast feeding at discharge
Breast feeding with supplemental feeds by other than bottle vs breast feeding with supplemental feeds by bottle (all trials)
RR 1.11 [1.06, 1.16]6 studies · 1138 participantsModerate
Downgraded: risk of bias
Any breast feeding at 3 months post discharge
Breast feeding with supplemental feeds by other than bottle vs breast feeding with supplemental feeds by bottle (all trials)
RR 1.31 [1.01, 1.71]5 studies · 1063 participantsVery low
Downgraded: risk of bias
Any breast feeding at 6 months post discharge
Breast feeding with supplemental feeds by other than bottle vs breast feeding with supplemental feeds by bottle (all trials)
RR 1.25 [1.1, 1.41]3 studies · 886 participantsVery low
Downgraded: risk of bias
Length of hospital stay
Breast feeding with supplemental feeds by other than bottle vs breast feeding with supplemental feeds by bottle (all trials)
no estimate extracted4 studies · 1004 participantsVery low
Downgraded: risk of bias
Episodes of infection
Breast feeding with supplemental feeds by other than bottle vs breast feeding with supplemental feeds by bottle (all trials)
RR 0.7 [0.35, 1.42]3 studies · 500 participantsModerate
Downgraded: risk of bias

Breast feeding with supplemental feeds by other than bottle compared with breast feeding with supplemental feeds by bottle (all trials) in preterm infants

Population: preterm infants
CD005252.PUB3 · 8 questions
OutcomeEffectEvidenceStatus / GRADE
Full breast feeding at discharge
Breast feeding with supplemental feeds by other than bottle vs breast feeding with supplemental feeds by bottle (all trials)
RR 1.47 [1.19, 1.8]6 studies · 1074 participantsLow
Downgraded: risk of bias
Full breast feeding at 3 months post discharge
Breast feeding with supplemental feeds by other than bottle vs breast feeding with supplemental feeds by bottle (all trials)
RR 1.56 [1.37, 1.78]4 studies · 986 participantsModerate
Downgraded: risk of bias
Full breast feeding at 6 months post discharge
Breast feeding with supplemental feeds by other than bottle vs breast feeding with supplemental feeds by bottle (all trials)
RR 1.64 [1.14, 2.36]3 studies · 887 participantsLow
Downgraded: risk of bias
Any breast feeding at discharge
Breast feeding with supplemental feeds by other than bottle vs breast feeding with supplemental feeds by bottle (all trials)
RR 1.11 [1.06, 1.16]6 studies · 1138 participantsModerate
Downgraded: risk of bias
Any breast feeding at 3 months post discharge
Breast feeding with supplemental feeds by other than bottle vs breast feeding with supplemental feeds by bottle (all trials)
RR 1.31 [1.01, 1.71]5 studies · 1063 participantsVery low
Downgraded: risk of bias
Any breast feeding at 6 months post discharge
Breast feeding with supplemental feeds by other than bottle vs breast feeding with supplemental feeds by bottle (all trials)
RR 1.25 [1.1, 1.41]3 studies · 886 participantsVery low
Downgraded: risk of bias
Length of hospital stay
Breast feeding with supplemental feeds by other than bottle vs breast feeding with supplemental feeds by bottle (all trials)
no estimate extracted4 studies · 1004 participantsVery low
Downgraded: risk of bias
Episodes of infection
Breast feeding with supplemental feeds by other than bottle vs breast feeding with supplemental feeds by bottle (all trials)
RR 0.7 [0.35, 1.42]3 studies · 500 participantsModerate
Downgraded: risk of bias