Cochrane · systematic review · CD005085
Oximes for acute organophosphate pesticide poisoning
Buckley, NA, Eddleston, M, Li, Y, et al. · Cochrane Database of Systematic Reviews · 2011 · Cochrane Library
InjuriesAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 6 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Oxime compared to placebo for acute organophosphate pesticide poisoning
Population: patients with acute organophosphate pesticide poisoning
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Deaths Oxime vs placebo | OR 2.68 [0.93, 7.72] | 3 studies · 366 participants | Very low Downgraded: risk of bias, imprecision, publication bias |
Intermediate syndrome Oxime vs placebo | OR 3.4 [1.62, 7.17] | 1 study · 110 participants | Very low Downgraded: risk of bias, imprecision |
Ventilated Oxime vs placebo | OR 2 [0.81, 4.95] | 3 studies · 366 participants | Very low Downgraded: risk of bias, imprecision, publication bias |
Higher dose compared to lower dose for acute organophosphate pesticide poisoning
Population: patients with acute organophosphate pesticide poisoning
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Deaths Higher dose vs lower dose | OR 0.38 [0.1, 1.47] | 4 studies · 479 participants | Very low Downgraded: risk of bias, imprecision, publication bias |
Intermediate syndrome Higher dose vs lower dose | OR 0.94 [0.24, 3.62] | 3 studies · 283 participants | Very low Downgraded: risk of bias, imprecision |
Ventilated Higher dose vs lower dose | OR 0.72 [0.08, 6.35] | 2 studies · 272 participants | Very low Downgraded: risk of bias, imprecision |