Cochrane · systematic review · CD005073
Uterine artery embolization for symptomatic uterine fibroids
Gupta, JK, Sinha, A, Lumsden, MA, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 14.3%Low 1 · 14.3%Moderate 5 · 71.4%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyUterine artery embolization (UAE) compared to surgery for symptomatic uterine fibroids
Population: women with symptomatic uterine fibroids
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Satisfaction with treatment up to 24 months Uterine artery embolization (UAE) vs surgery | OR 0.94 [0.59, 1.48] | 6 studies · 640 participants | Moderate |
Satisfaction with treatment at 5 years Uterine artery embolization (UAE) vs surgery | OR 0.9 [0.45, 1.8] | 2 studies · 295 participants | Moderate |
Live birth ‐ UAE versus myomectomy Uterine artery embolization (UAE) vs surgery | OR 0.26 [0.08, 0.84] | 1 study · 66 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Adverse events: intra‐procedural complications Uterine artery embolization (UAE) vs surgery | OR 0.91 [0.42, 1.97] | 4 studies · 452 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Adverse events: minor post‐procedural complications within one year Uterine artery embolization (UAE) vs surgery | OR 1.99 [1.41, 2.81] | 6 studies · 735 participants | Moderate |
Adverse events: major post‐procedural complications within one year Uterine artery embolization (UAE) vs surgery | OR 0.65 [0.33, 1.26] | 5 studies · 611 participants | Moderate |
Further interventions within 2 years Uterine artery embolization (UAE) vs surgery | OR 3.72 [2.28, 6.04] | 6 studies · 732 participants | Moderate |
UAE compared to surgery for symptomatic uterine fibroids
Population: patients with symptomatic uterine fibroids
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Satisfaction with treatment at 5 years UAE vs surgery | OR 0.9 [0.45, 1.8] | 2 studies · 295 participants | Moderate Downgraded: risk of bias |
Live birth ‐ UAE versus myomectomy UAE vs surgery | OR 0.33 [0.11, 1] | 1 study · 66 participants | Very low Downgraded: risk of bias |
Pregnancy UAE vs surgery | OR 0.29 [0.1, 0.85] | 1 study · 66 participants | Very low Downgraded: risk of bias |
Fibroid recurrence within 2 years UAE vs surgery | OR 1.32 [0.38, 4.57] | 1 study · 120 participants | Very low Downgraded: risk of bias |
Adverse events: any complications within first month ‐ UAE versus myomectomy UAE vs surgery | OR 1.38 [0.55, 3.5] | 1 study · 121 participants | Low Downgraded: risk of bias |
Adverse events: major postprocedural complications UAE vs surgery | OR 0.71 [0.32, 1.58] | 2 studies · 264 participants | Moderate Downgraded: risk of bias |
Further interventions within 2 years UAE vs surgery | OR 5.09 [2.82, 9.18] | 5 studies · 649 participants | Moderate Downgraded: risk of bias |
Health related quality of life at 1 year UAE vs surgery | no estimate extracted | 1 study · 163 participants | Very low Downgraded: risk of bias |