Cochrane · systematic review · CD004985

Preoperative bathing or showering with skin antiseptics to prevent surgical site infection

Webster, J, Osborne, S · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library

Wounds3 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 50%Low 0 · 0%Moderate 1 · 25%High 1 · 25%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

Preoperative showering with chlorhexidine 4% compared to placebo

Population: surgical patients
CD004985.PUB5 (current) · 2 questions
OutcomeEffectEvidenceStatus / GRADE
Surgical site infection
Preoperative showering with chlorhexidine 4% vs placebo
RR 0.91 [0.8, 1.04]4 studies · 7791 participantsHigh
Allergic reaction
Preoperative showering with chlorhexidine 4% vs placebo
RR 0.89 [0.36, 2.19]2 studies · 3589 participantsModerate

Chlorhexidine 4% compared with bar soap

Population: Surgical patients
CD004985.PUB5 (current) · 1 question
OutcomeEffectEvidenceStatus / GRADE
Surgical site infection
Chlorhexidine 4% vs bar soap
RR 1.02 [0.57, 1.84]3 studies · 1443 participantsVery low
Downgraded: risk of bias, inconsistency

Chlorhexadine 4% compared with no wash

Population: surgical patients
CD004985.PUB5 (current) · 1 question
OutcomeEffectEvidenceStatus / GRADE
Surgical site infection
Chlorhexadine 4% vs no wash
RR 0.82 [0.26, 2.62]3 studies · 1142 participantsVery low
Downgraded: risk of bias, imprecision

Preoperative showering with chlorhexidine 4% compared to placebo

Population: surgical patients
CD004985.PUB4 · 2 questions
OutcomeEffectEvidenceStatus / GRADE
Surgical site infection
Preoperative showering with chlorhexidine 4% vs placebo
RR 0.91 [0.8, 1.04]4 studies · 7791 participantsHigh
Allergic reaction
Preoperative showering with chlorhexidine 4% vs placebo
RR 0.89 [0.36, 2.19]2 studies · 3589 participantsModerate

Chlorhexidine 4% compared with bar soap

Population: Surgical patients
CD004985.PUB4 · 1 question
OutcomeEffectEvidenceStatus / GRADE
Surgical site infection
Chlorhexidine 4% vs bar soap
RR 1.02 [0.57, 1.84]3 studies · 1443 participantsVery low
Downgraded: risk of bias, inconsistency

Chlorhexadine 4% compared with no wash

Population: surgical patients
CD004985.PUB4 · 1 question
OutcomeEffectEvidenceStatus / GRADE
Surgical site infection
Chlorhexadine 4% vs no wash
RR 0.82 [0.26, 2.62]3 studies · 1142 participantsVery low
Downgraded: risk of bias, imprecision

Preoperative showering with chlorhexidine 4% compared to placebo

Population: surgical patients
CD004985.PUB3 · 2 questions
OutcomeEffectEvidenceStatus / GRADE
Surgical site infection
Preoperative showering with chlorhexidine 4% vs placebo
RR 0.91 [0.8, 1.04]4 studies · 7791 participantsHigh
Allergic reaction
Preoperative showering with chlorhexidine 4% vs placebo
RR 0.89 [0.36, 2.19]2 studies · 3589 participantsModerate

Chlorhexidine 4% compared with bar soap

Population: surgical patients
CD004985.PUB3 · 1 question
OutcomeEffectEvidenceStatus / GRADE
Surgical site infection
Chlorhexidine 4% vs bar soap
RR 1.02 [0.57, 1.84]3 studies · 1443 participantsVery low
Downgraded: risk of bias, inconsistency

Chlorhexadine 4% compared with no wash

Population: surgical patients
CD004985.PUB3 · 1 question
OutcomeEffectEvidenceStatus / GRADE
Surgical site infection
Chlorhexadine 4% vs no wash
RR 0.82 [0.26, 2.62]3 studies · 1142 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency