Cochrane · systematic review · CD004905

Multiple‐micronutrient supplementation for women during pregnancy

Keats, EC, Haider, BA, Tam, E, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library

Pregnancy and Childbirth3 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 33.3%High 4 · 66.7%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 3 versions

Multiple micronutrients compared to control (iron with or without folic acid) for women during pregnancy

Population: women during pregnancy
6 questions
OutcomeEffectEvidenceStatus / GRADE
Preterm births
Multiple micronutrients vs control (iron with or without folic acid)
RR 0.95 [0.9, 1.01]18 studies · 91425 participantsModerate
Downgraded: publication bias
Small‐for‐gestational age
Multiple micronutrients vs control (iron with or without folic acid)
RR 0.92 [0.88, 0.97]17 studies · 57348 participantsModerate
Downgraded: publication bias
Low birthweight
Multiple micronutrients vs control (iron with or without folic acid)
RR 0.88 [0.85, 0.91]18 studies · 68801 participantsHigh
Perinatal mortality
Multiple micronutrients vs control (iron with or without folic acid)
RR 1 [0.9, 1.11]15 studies · 63922 participantsHigh
Stillbirths
Multiple micronutrients vs control (iron with or without folic acid)
RR 0.95 [0.86, 1.04]17 studies · 97927 participantsHigh
Neonatal mortality
Multiple micronutrients vs control (iron with or without folic acid)
RR 1 [0.89, 1.12]14 studies · 80964 participantsHigh