Cochrane · systematic review · CD004868
Late erythropoiesis‐stimulating agents to prevent red blood cell transfusion in preterm or low birth weight infants
Aher, SM, Ohlsson, A · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 3 · 60%Low 0 · 0%Moderate 2 · 40%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyComparison
Population: preterm infants with low birth weight
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Use of one or more red blood cell transfusions (low and high dose of EPO) during initial hospital stay | RR 0.72 [0.65, 0.79] | 21 studies · 1202 participants | Very low |
Necrotising Enterocolitis ≥ Bell's stage 2 during initial hospital stay | RR 0.88 [0.45, 1.7] | 6 studies · 656 participants | Moderate |
Mortality during initial hospital stay (all causes) | RR 0.82 [0.49, 1.39] | 14 studies · 767 participants | Moderate |
Retinopathy of prematurity (all stages or stage not reported) during initial hospital stay | RR 1.27 [0.99, 1.64] | 3 studies · 404 participants | Very low |
Retinopathy of prematurity (stage ≥ 3) during initial hospital stay | RR 1.73 [0.92, 3.24] | 3 studies · 442 participants | Very low |
Comparison
Population: preterm infants with low birth weight
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Use of one or more red blood cell transfusions (low and high dose of EPO) during initial hospital stay | RR 0.72 [0.65, 0.79] | 21 studies · 1202 participants | Very low |
Necrotising Enterocolitis ≥ Bell's stage 2 during initial hospital stay | RR 0.88 [0.45, 1.7] | 6 studies · 656 participants | Moderate |
Mortality during initial hospital stay (all causes) | RR 0.82 [0.49, 1.39] | 14 studies · 767 participants | Moderate |
Retinopathy of prematurity (all stages or stage not reported) during initial hospital stay | RR 1.27 [0.99, 1.64] | 3 studies · 404 participants | Very low |
Retinopathy of prematurity (stage ≥ 3) during initial hospital stay | RR 1.73 [0.92, 3.24] | 3 studies · 442 participants | Very low |