Cochrane · systematic review · CD004711

Heat and moisture exchangers versus heated humidifiers for mechanically ventilated adults and children

Gillies, D, Todd, DA, Foster, JP, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library

Emergency and Critical Care2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 100%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

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Heat and moisture exchangers (HME) compared to heated humidifiers (HH) for ventilated adults and children

Population: ventilated adults (18 trials) and children (1 trial)
3 questions
OutcomeEffectEvidenceStatus / GRADE
Artificial airway occlusion (measured over 3‐15 days (median 4 days))
Heat and moisture exchangers (HME) vs heated humidifiers (HH)
RR 1.59 [0.6, 4.19]15 studies · 2171 participantsLow
Downgraded: indirectness
Mortality ‐ all cause (Measured over 3‐15 days (median 8 days))
Heat and moisture exchangers (HME) vs heated humidifiers (HH)
RR 1.03 [0.89, 1.2]12 studies · 1951 participantsLow
Downgraded: indirectness
Pneumonia (Measured over 4‐21 days (median 4 days))
Heat and moisture exchangers (HME) vs heated humidifiers (HH)
RR 0.93 [0.73, 1.19]13 studies · 2251 participantsLow
Downgraded: indirectness