Cochrane · systematic review · CD004690
Cognitive behavioural therapy for anxiety disorders in children and adolescents
James, AC, James, G, Cowdrey, FA, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
9
current version
GRADE rated
9
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 4 · 44.4%Moderate 5 · 55.6%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyCBT compared to wait‐list for children and adolescents with anxiety disorders
Population: children and adolescents with anxiety disorders
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Remission of anxiety diagnoses (ITT analysis) i.e. no longer meeting criteria for DSM or ICD anxiety diagnosis at the end of the trial. CBT vs wait‐list | OR 7.85 [5.31, 11.6] | 26 studies · 1350 participants | Moderate Downgraded: inconsistency |
Participants lost to CBT vs wait‐list | OR 0.94 [0.58, 1.51] | 26 studies · 1297 participants | Low Downgraded: imprecision |
Reduction in anxiety symptoms at the end of the trial CBT vs wait‐list | no estimate extracted | 30 studies · 1394 participants | Low Downgraded: inconsistency |
Remission of anxiety diagnoses: long‐term CBT vs wait‐list | OR 3.22 [0.96, 10.75] | 3 studies · 124 participants | Low Downgraded: imprecision, inconsistency |
Reduction in anxiety symptoms: long‐term CBT vs wait‐list | no estimate extracted | 4 studies · 186 participants | Low Downgraded: imprecision, inconsistency |
CBT compared to active controls for children and adolescents with anxiety disorder
Population: children and adolescents with anxiety disorders
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Remission of anxiety diagnoses (ITT) analysis i.e. no longer meeting criteria for DSM or ICD anxiety diagnosis at the end of the trial. CBT vs active controls | OR 1.51 [0.77, 2.96] | 6 studies · 426 participants | Moderate |
Reduction in anxiety symptoms at the end of the trial CBT vs active controls | no estimate extracted | 8 studies · 411 participants | Moderate Downgraded: imprecision, inconsistency |
CBT compared to treatment as usual (TAU) for children and adolescents with anxiety disorder
Population: children and adolescents with anxiety disorders
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Remission of anxiety diagnoses (ITT analysis) i.e. no longer meeting criteria for DSM or ICD anxiety diagnosis at the end of the trial. CBT vs treatment | OR 0.53 [0.23, 1.25] | 2 studies · 88 participants | Moderate Downgraded: imprecision |
Reduction of anxiety symptoms at the end of the trial CBT vs treatment | no estimate extracted | 3 studies · 98 participants | Moderate Downgraded: imprecision, inconsistency |
CBT compared to wait‐list for children and adolescents with anxiety disorders
Population: children and adolescents with anxiety disorders
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Remission of anxiety diagnoses (ITT analysis), i.e. no longer meeting criteria for DSM or ICD anxiety diagnosis at the end of the trial CBT vs wait‐list | OR 0.13 [0.06, 0.26] | 26 studies · 1350 participants | Moderate Downgraded: inconsistency |
Participants lost to CBT vs wait‐list | OR 0.93 [0.58, 1.51] | 26 studies · 1297 participants | Low Downgraded: imprecision |
Reduction in anxiety symptoms at the end of the trial CBT vs wait‐list | no estimate extracted | 30 studies · 1394 participants | Low Downgraded: inconsistency |
Remission of anxiety diagnoses: long‐term CBT vs wait‐list | OR 0.31 [0.09, 1.04] | 3 studies · 124 participants | Low Downgraded: imprecision, inconsistency |
Reduction in anxiety symptoms: long‐term CBT vs wait‐list | no estimate extracted | 4 studies · 171 participants | Low Downgraded: imprecision, inconsistency |
CBT compared to active controls for children and adolescents with anxiety disorders
Population: children and adolescents with anxiety disorders
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Remission of anxiety diagnoses (ITT analysis), i.e. no longer meeting criteria for DSM or ICD anxiety diagnosis at the end of the trial CBT vs active controls | OR 0.66 [0.34, 1.29] | 6 studies · 426 participants | Moderate |
Reduction in anxiety symptoms at the end of the trial CBT vs active controls | no estimate extracted | 8 studies · 411 participants | Moderate Downgraded: imprecision, inconsistency |
CBT compared to treatment as usual (TAU) for children and adolescents with anxiety disorders
Population: children and adolescents with anxiety disorders
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Remission of anxiety diagnoses (ITT analysis), i.e. no longer meeting criteria for DSM or ICD anxiety diagnosis at the end of the trial CBT vs treatment | OR 1.87 [0.8, 4.39] | 2 studies · 88 participants | Moderate Downgraded: imprecision |
Reduction of anxiety symptoms at the end of the trial CBT vs treatment | no estimate extracted | 3 studies · 98 participants | Moderate Downgraded: imprecision, inconsistency |