Cochrane · systematic review · CD004127
Noninvasive positive‐pressure ventilation as a weaning strategy for intubated adults with respiratory failure
Burns, KEA, Meade, MO, Premji, A, et al. · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library
Emergency and Critical CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 50%Moderate 3 · 50%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Noninvasive versus invasive weaning for intubated adults with respiratory failure
Population: intubated adults with respiratory failure
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality—COPD Noninvasive vs invasive weaning | RR 0.36 [0.24, 0.56] | 9 studies · 632 participants | Moderate |
Mortality—mixed Noninvasive vs invasive weaning | RR 0.81 [0.47, 1.4] | 7 studies · 362 participants | Low |
Noninvasive versus invasive weaning for intubated adults with respiratory failure
Population: patients with intubated adults with respiratory failure
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Weaning failure Noninvasive vs invasive weaning | RR 0.63 [0.42, 0.96] | 8 studies · 605 participants | Moderate |
Nosocomial pneumonia Noninvasive vs invasive weaning | RR 0.25 [0.15, 0.43] | 14 studies · 953 participants | Low |
Average duration of ventilation related to weaning Noninvasive vs invasive weaning | no estimate extracted | 9 studies · 645 participants | Low Downgraded: inconsistency |
Reintubation Noninvasive vs invasive weaning | RR 0.65 [0.44, 0.97] | 10 studies · 789 participants | Moderate |