Cochrane · systematic review · CD004085

High‐frequency oscillatory ventilation versus conventional ventilation for acute respiratory distress syndrome

Sud, S, Sud, M, Friedrich, JO, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

Emergency and Critical Care2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
1
Included studies
NR
No studies 1 · 14.3%Ungraded 0 · 0%Very low 6 · 85.7%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

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High‐frequency oscillation versus conventional ventilation for the treatment of acute respiratory distress syndrome

Population: people with Acute Respiratory Distress Syndrome
7 questions
OutcomeEffectEvidenceStatus / GRADE
Outcomes**
High‐frequency oscillation vs conventional ventilation
no estimate extractedNRNo studies
Mortality (at 30 days or until hospital discharge)
High‐frequency oscillation vs conventional ventilation
RR 0.92 [0.72, 1.16]8 studies · 1779 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Mortality (at 6 months)
High‐frequency oscillation vs conventional ventilation
RR 0.79 [0.58, 1.08]1 study · 148 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Treatment failure
High‐frequency oscillation vs conventional ventilation
RR 0.64 [0.48, 0.85]6 studies · 956 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Duration of mechanical ventilation days. Scale from: 14 to 22
High‐frequency oscillation vs conventional ventilation
no estimate extracted5 studies · 1142 participantsVery low
Downgraded: imprecision, indirectness
Barotrauma
High‐frequency oscillation vs conventional ventilation
RR 0.82 [0.51, 1.32]7 studies · 951 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Hypotension
High‐frequency oscillation vs conventional ventilation
RR 1.02 [0.54, 1.9]4 studies · 392 participantsVery low
Downgraded: risk of bias, imprecision, indirectness