Cochrane · systematic review · CD003968

Psychological therapies for the management of chronic and recurrent pain in children and adolescents

Fisher, E, Law, E, Dudeney, J, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

Pain, Palliative and Supportive Care3 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
15
current version
GRADE rated
14
No studies
1
Included studies
NR
No studies 1 · 6.7%Ungraded 0 · 0%Very low 10 · 66.7%Low 4 · 26.7%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

Summary of findings

Population: Children and adolescents with chronic pain
CD003968.PUB5 (current) · 7 questions
OutcomeEffectEvidenceStatus / GRADE
Pain: 50% reduction in headache frequency Post‐treatment Lower scores = fewer headaches
RR 2.35 [1.67, 3.3]15 studies · 644 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, publication bias
Pain: 50% reduction in headache frequency
RR 2.73 [0.98, 7.63]5 studies · 223 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, publication bias
Disability Post‐treatment Lower scores = lower reported disability
no estimate extracted6 studies · 446 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, publication bias
Disability
no estimate extracted3 studies · 209 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, publication bias
Anxiety Post‐treatment Lower scores = lower reported anxiety
no estimate extracted7 studies · 439 participantsVery low
Downgraded: risk of bias
Anxiety
no estimate extracted4 studies · 271 participantsVery low
Downgraded: risk of bias
Depression Post‐treatment Lower scores = lower reported depression
no estimate extracted6 studies · 400 participantsVery low
Downgraded: risk of bias

Summary of findings

Population: Children and adolescents with chronic pain
CD003968.PUB5 (current) · 8 questions
OutcomeEffectEvidenceStatus / GRADE
Pain Post‐treatment Lower scores = lower reported pain intensity
no estimate extracted16 studies · 1210 participantsVery low
Downgraded: risk of bias, inconsistency, publication bias
Pain
no estimate extracted9 studies · 763 participantsVery low
Downgraded: risk of bias, inconsistency, publication bias
Disability Post‐treatment Lower scores = lower reported disability
no estimate extracted14 studies · 1226 participantsLow
Downgraded: risk of bias, inconsistency, publication bias
Disability
no estimate extracted9 studies · 866 participantsLow
Downgraded: risk of bias, inconsistency, publication bias
Anxiety Post‐treatment Lower scores = lower reported anxiety
no estimate extracted8 studies · 883 participantsLow
Downgraded: risk of bias, inconsistency, publication bias
Anxiety
no estimate extracted8 studies · 805 participantsLow
Downgraded: risk of bias, inconsistency, publication bias
Depression Post‐treatment Lower scores = lower reported depression
no estimate extracted8 studies · 757 participantsVery low
Downgraded: risk of bias, inconsistency, publication bias
CI: Confidence interval.
no estimate extractedNRNo studies

Comparison

Population: children and adolescents with frequent headache
CD003968.PUB4 · 7 questions
OutcomeEffectEvidenceStatus / GRADE
Pain (low scores mean lower pain ratings)
RR 2.47 [1.97, 3.09]15 studies · 714 participantsLow
Pain (at
RR 2.89 [1.03, 8.07]5 studies · 251 participantsVery low
Disability (low scores mean lower disability ratings)
no estimate extracted3 studies · 263 participantsLow
Disability (at
no estimate extracted2 studies · 148 participantsLow
Depression (low scores mean lower depression ratings)
no estimate extracted3 studies · 164 participantsModerate
Anxiety (low scores mean lower anxiety ratings)
no estimate extracted4 studies · 203 participantsLow
Anxiety (at
no estimate extracted2 studies · 67 participantsVery low

Comparison

Population: children and adolescents with non‐headache pain
CD003968.PUB4 · 7 questions
OutcomeEffectEvidenceStatus / GRADE
Pain (low scores mean lower pain ratings)
no estimate extracted13 studies · 852 participantsVery low
Pain (at
no estimate extracted7 studies · 543 participantsLow
Disability (low scores mean lower disability ratings)
no estimate extracted11 studies · 764 participantsVery low
Disability (at
no estimate extracted6 studies · 508 participantsLow
Depression (low scores mean lower depression ratings)
no estimate extracted6 studies · 538 participantsModerate
Depression (at
no estimate extracted5 studies · 473 participantsModerate
Anxiety (low scores mean lower anxiety ratings)
no estimate extracted5 studies · 498 participantsModerate

Psychological therapies for the management of chronic pain (headache) in children and adolescents

Population: patients with the management of chronic and recurrent pain in children and adolescents
CD003968.PUB3 · 6 questions
OutcomeEffectEvidenceStatus / GRADE
Pain
RR 2.9 [2.25, 3.73]18 studies · 748 participantsModerate
Pain (at
RR 3.34 [2.01, 5.53]6 studies · 196 participantsLow
Downgraded: imprecision
Disability
no estimate extracted3 studies · 108 participantsModerate
Downgraded: inconsistency
Disability (at
no estimate extracted1 study · 24 participantsLow
Downgraded: imprecision
Mood
no estimate extracted5 studies · 204 participantsHigh
Mood (at
no estimate extracted2 studies · 59 participantsModerate
Downgraded: imprecision

Psychological therapies for the management of chronic (non‐headache) in children and adolescents

Population: Children and adolescents with chronic pain (non‐headache)
CD003968.PUB3 · 6 questions
OutcomeEffectEvidenceStatus / GRADE
Pain
no estimate extracted12 studies · 709 participantsModerate
Downgraded: inconsistency
Pain (at
no estimate extracted5 studies · 357 participantsModerate
Downgraded: inconsistency
Disability
no estimate extracted9 studies · 588 participantsHigh
Disability (at
no estimate extracted3 studies · 292 participantsHigh
Mood
no estimate extracted6 studies · 435 participantsModerate
Downgraded: inconsistency
Mood (at
no estimate extracted3 studies · 292 participantsHigh