Cochrane · systematic review · CD003906
Plasma exchange for chronic inflammatory demyelinating polyradiculoneuropathy
Mehndiratta, MM, Hughes, RAC, Pritchard, J · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
3
No studies
1
Included studies
NR
No studies 1 · 20%Ungraded 1 · 20%Very low 0 · 0%Low 0 · 0%Moderate 2 · 40%High 1 · 20%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyPlasma exchange versus sham exchange for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP)
Population: people with CIDP
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Change in disability after 4 weeks disability grade change. Scale from: 0 to 10; lower is better Plasma exchange vs sham exchange | no estimate extracted | 1 study · 36 participants | Moderate |
Change in impairment (NIS) after 4 weeks NIS score points. Scale from: 0 to 280; lower is better Plasma exchange vs sham exchange | no estimate extracted | 2 studies · 59 participants | High |
Change in mean compound muscle action potential amplitude after 4 weeks mA Plasma exchange vs sham exchange | no estimate extracted | 1 study · 30 participants | Moderate |
Serious adverse events ‐ not measured Plasma exchange vs sham exchange | no estimate extracted | NR | No studies |
Only 1 trial. Plasma exchange vs sham exchange | no estimate extracted | 1 study · 1 participants | Ungraded |
Plasma exchange versus sham exchange for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP)
Population: patients with CIDP
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Change in disability after 4 weeks disability grade change. Scale from: 0 to 10. Plasma exchange vs sham exchange | no estimate extracted | 1 study · 30 participants | Moderate |
Change in impairment (NIS) after 4 weeks NIS score points. Scale from: 0 to 280. Plasma exchange vs sham exchange | no estimate extracted | 2 studies · 59 participants | High |
Change in mean compound muscle action potential amplitude after 4 weeks mA. Scale from: 0 to 10. Plasma exchange vs sham exchange | no estimate extracted | 1 study · 30 participants | Moderate |
Serious adverse events ‐ not measured Plasma exchange vs sham exchange | no estimate extracted | NR | No studies |
Only 1 trial. Plasma exchange vs sham exchange | no estimate extracted | 1 study · 1 participants | Ungraded |
Plasma exchange versus sham exchange for chronic inflammatory demyelinating polyradiculoneuropathy
Population: patients with chronic inflammatory demyelinating polyradiculoneuropathy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Change in disability after 4 weeks disability grade change. Scale from: 0 to 10. Plasma exchange vs sham exchange | no estimate extracted | 1 study · 30 participants | Moderate |
Change in impairment (NDS) after 4 weeks NIS score points. Scale from: 0 to 200. Plasma exchange vs sham exchange | no estimate extracted | 2 studies · 59 participants | High |
Change in mean compound muscle action potential amplitude after 4 weeks mA. Scale from: 0 to 10. Plasma exchange vs sham exchange | no estimate extracted | 1 study · 30 participants | Moderate |
Serious adverse events ‐ not measured Plasma exchange vs sham exchange | no estimate extracted | NR | No studies |
Only 1 trial. Plasma exchange vs sham exchange | no estimate extracted | 1 study · 1 participants | Ungraded |