Cochrane · systematic review · CD003464
Antiplatelet and anticoagulation for patients with prosthetic heart valves
Massel, DR, Little, SH · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library
HeartAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 66.7%High 1 · 33.3%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Antiplatelet and oral anticoagulation against oral anticoagulation alone for prosthetic heart valves
Population: patients with prosthetic heart valves
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Thromboembolism | OR 0.43 [0.32, 0.59] | 13 studies · 4122 participants | High |
Mortality | OR 0.57 [0.42, 0.78] | 13 studies · 4122 participants | Moderate Downgraded: risk of bias |
Major Bleeding | OR 1.58 [1.14, 2.18] | 11 studies · 3856 participants | Moderate Downgraded: risk of bias |