Cochrane · systematic review · CD003310

Calcium and phosphorus supplementation of human milk for preterm infants

Harding, JE, Wilson, J, Brown, J · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library

NeonatalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
3
No studies
4
Included studies
NR
No studies 4 · 57.1%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 42.9%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Calcium supplementation compared with no calcium supplementation for preterm infants

Population: preterm hospitalised infants
7 questions
OutcomeEffectEvidenceStatus / GRADE
Weight (g) ‐ weight at 6 weeks
Calcium supplementation vs no calcium supplementation
no estimate extracted1 study · 40 participantsLow
Downgraded: risk of bias
Length (cm) ‐ length at 6 weeks
Calcium supplementation vs no calcium supplementation
no estimate extracted1 study · 40 participantsLow
Downgraded: risk of bias
Head circumference (cm) ‐ head circumference at 6 weeks
Calcium supplementation vs no calcium supplementation
no estimate extracted1 study · 40 participantsLow
Downgraded: risk of bias
Bone fracture (neonatal) ‐ not measured
Calcium supplementation vs no calcium supplementation
no estimate extractedNRNo studies
Growth (childhood/adulthood) ‐ not measured
Calcium supplementation vs no calcium supplementation
no estimate extractedNRNo studies
Bone mineral density (infant/childhood/adulthood) ‐ not measured
Calcium supplementation vs no calcium supplementation
no estimate extractedNRNo studies
Fracture (childhood/adulthood) ‐ not measured
Calcium supplementation vs no calcium supplementation
no estimate extractedNRNo studies