Cochrane · systematic review · CD002843

Strategies for partner notification for sexually transmitted infections, including HIV

Ferreira, A, Young, T, Mathews, C, et al. · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library

Sexually Transmitted InfectionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
11
current version
GRADE rated
11
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 8 · 72.7%Moderate 3 · 27.3%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Enhanced patient referral compared with simple patient referral for partner notification for STIs, including HIV

5 questions
OutcomeEffectEvidenceStatus / GRADE
Re‐infection in index patient ‐ home sampling vs. simple patient referral
Enhanced patient referral vs simple patient referral
RR 2.14 [0.91, 5.05]1 study · 220 participantsLow
Downgraded: risk of bias, imprecision
Re‐infection in index patient ‐ information booklet vs. simple patient referral
Enhanced patient referral vs simple patient referral
RR 0.55 [0.22, 1.33]2 studies · 942 participantsLow
Downgraded: risk of bias
Re‐infection in index patient ‐ patient referral (DIS/health advisor) vs. patient referral (nurse)
Enhanced patient referral vs simple patient referral
RR 0.35 [0.01, 8.51]1 study · 140 participantsLow
Downgraded: imprecision
Re‐infection in index patient ‐ disease‐specific website vs. simple referral
Enhanced patient referral vs simple patient referral
RR 3.12 [0.17, 58.73]1 study · 105 participantsLow
Downgraded: imprecision
Re‐infection in index patient ‐ additional counselling vs. simple patient referral
Enhanced patient referral vs simple patient referral
RR 0.49 [0.27, 0.89]1 study · 600 participantsModerate
Downgraded: risk of bias

Expedited partner therapy compared with simple patient referral for partner notification for STIs, including HIV

4 questions
OutcomeEffectEvidenceStatus / GRADE
Re‐infection in index patients
Expedited partner therapy vs simple patient referral
RR 0.71 [0.56, 0.89]6 studies · 6018 participantsModerate
Downgraded: risk of bias
Re‐infection in index patients ‐ chlamydia
Expedited partner therapy vs simple patient referral
RR 0.9 [0.6, 1.35]2 studies · 2007 participantsModerate
Re‐infection in index patients ‐ trichomonas
Expedited partner therapy vs simple patient referral
RR 0.67 [0.34, 1.28]2 studies · 631 participantsLow
Downgraded: risk of bias, imprecision
Re‐infection in index patients ‐ chlamydia or gonorrhoea
Expedited partner therapy vs simple patient referral
RR 0.61 [0.39, 0.94]2 studies · 3380 participantsLow
Downgraded: risk of bias

Expedited partner therapy compared with enhanced patient referral for partner notification for STIs, including HIV

1 question
OutcomeEffectEvidenceStatus / GRADE
EPT vs. enhanced patient referral ‐ re‐infection in index patients
Expedited partner therapy vs enhanced patient referral
RR 0.96 [0.6, 1.53]3 studies · 1220 participantsLow
Downgraded: risk of bias, imprecision

Contract referral compared with expedited partner therapy for partner notification for STIs, including HIV

1 question
OutcomeEffectEvidenceStatus / GRADE
Re‐infection in index patient
Contract referral vs expedited partner therapy
RR 2 [0.7, 5.72]1 study · 322 participantsLow
Downgraded: risk of bias, imprecision