Cochrane · systematic review · CD001333
Oral naltrexone maintenance treatment for opioid dependence
Minozzi, S, Amato, L, Vecchi, S, et al. · Cochrane Database of Systematic Reviews · 2011 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
0
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 3 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlynaltrexone versus placebo or no pharmacological treatments for opioid dependence
Population: patients with opioid dependence
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
retention and abstinence, all patients naltrexone vs placebo or no pharmacological treatments | RR 1.43 [0.72, 2.82] | 6 studies · 393 participants | Ungraded |
abstinence at naltrexone vs placebo or no pharmacological treatments | RR 1.28 [0.8, 2.05] | 3 studies · 116 participants | Ungraded |
side effects naltrexone vs placebo or no pharmacological treatments | RR 1.29 [0.54, 3.11] | 4 studies · 159 participants | Ungraded |
naltrexone versus placebo or no pharmacological treatments for opioid dependence
Population: patients with opioid dependence
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
retention and abstinence, all patients naltrexone vs placebo or no pharmacological treatments | RR 1.43 [0.72, 2.82] | 6 studies · 393 participants | Ungraded |
abstinence at naltrexone vs placebo or no pharmacological treatments | RR 1.28 [0.8, 2.05] | 3 studies · 116 participants | Ungraded |
side effects naltrexone vs placebo or no pharmacological treatments | RR 1.29 [0.54, 3.11] | 4 studies · 159 participants | Ungraded |