Cochrane · systematic review · CD000341

Fat supplementation of human milk for promoting growth in preterm infants

Amissah, EA, Brown, J, Harding, JE · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library

Neonatal2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
4
No studies
3
Included studies
NR
No studies 3 · 42.9%Ungraded 0 · 0%Very low 4 · 57.1%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

Fat supplementation compared to control for promoting growth in preterm infants

Population: preterm infants
CD000341.PUB3 (current) · 7 questions
OutcomeEffectEvidenceStatus / GRADE
Growth ‐ weight ‐ weight gain (g/kg/day)
Fat supplementation vs control
no estimate extracted1 study · 14 participantsVery low
Downgraded: risk of bias
Growth ‐ length ‐ length gain (cm/week)
Fat supplementation vs control
no estimate extracted1 study · 14 participantsVery low
Downgraded: risk of bias
Growth ‐ head circumference ‐ head growth (cm/week)
Fat supplementation vs control
no estimate extracted1 study · 14 participantsVery low
Downgraded: risk of bias
Neurodevelopmental outcomes
Fat supplementation vs control
no estimate extractedNRNo studies
Duration of hospital admission (days)
Fat supplementation vs control
no estimate extractedNRNo studies
Feeding intolerance
Fat supplementation vs control
RR 3 [0.1, 64.3]1 study · 16 participantsVery low
Downgraded: risk of bias
Necrotising enterocolitis
Fat supplementation vs control
no estimate extractedNRNo studies

Fat supplementation compared to control for promoting growth in preterm infants

Population: preterm infants
CD000341.PUB2 · 7 questions
OutcomeEffectEvidenceStatus / GRADE
Growth ‐ weight ‐ weight gain (g/kg/day)
Fat supplementation vs control
no estimate extracted1 study · 14 participantsVery low
Downgraded: risk of bias
Growth ‐ length ‐ length gain (cm/week)
Fat supplementation vs control
no estimate extracted1 study · 14 participantsVery low
Downgraded: risk of bias
Growth ‐ head circumference ‐ head growth (cm/week)
Fat supplementation vs control
no estimate extracted1 study · 14 participantsVery low
Downgraded: risk of bias
Neurodevelopmental outcomes
Fat supplementation vs control
no estimate extractedNRNo studies
Duration of hospital admission (days)
Fat supplementation vs control
no estimate extractedNRNo studies
Feeding intolerance
Fat supplementation vs control
RR 3 [0.1, 64.3]1 study · 16 participantsVery low
Downgraded: risk of bias
Necrotising enterocolitis
Fat supplementation vs control
no estimate extractedNRNo studies