Cochrane · systematic review · CD000103

Haemodilution for acute ischaemic stroke

Chang, TS, Jensen, MB · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library

StrokeAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 16.7%Moderate 5 · 83.3%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Haemodilution, all types, versus control for acute ischaemic stroke

Population: people with acute ischaemic stroke
6 questions
OutcomeEffectEvidenceStatus / GRADE
Mortality at early
Haemodilution, all types, vs control
RR 1.1 [0.9, 1.34]16 studies · 3866 participantsModerate
Downgraded: risk of bias
Mortality at late
Haemodilution, all types, vs control
RR 1.05 [0.93, 1.2]15 studies · 3957 participantsModerate
Downgraded: risk of bias
Dead or dependent/institutionalised at 3‐6 months
Haemodilution, all types, vs control
RR 0.96 [0.85, 1.07]8 studies · 2491 participantsModerate
Downgraded: risk of bias
Venous thromboembolic events at early
Haemodilution, all types, vs control
RR 0.83 [0.2, 3.44]4 studies · 621 participantsModerate
Venous thromboembolic events at late
Haemodilution, all types, vs control
RR 0.68 [0.37, 1.24]6 studies · 865 participantsModerate
Serious cardiac events, cumulative at latest
Haemodilution, all types, vs control
RR 1.16 [0.66, 2.05]7 studies · 1358 participantsLow
Downgraded: risk of bias, imprecision