Cochrane · systematic review · CD000024
Anticoagulants for acute ischaemic stroke
Wang, X, Ouyang, M, Yang, J, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
StrokeAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 14.3%Low 1 · 14.3%Moderate 3 · 42.9%High 2 · 28.6%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings table ‐ Anticoagulant compared to control in acute presumed ischaemic stroke
Population: acute presumed ischaemic stroke
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Dead or dependent at end of Summary of findings table ‐ Anticoagulant vs control | OR 0.98 [0.92, 1.03] | 13 studies · 22428 participants | High |
Death from all causes during treatment period Summary of findings table ‐ Anticoagulant vs control | OR 0.99 [0.9, 1.09] | 22 studies · 22602 participants | Low |
Deep vein thrombosis during treatment period Summary of findings table ‐ Anticoagulant vs control | OR 0.21 [0.15, 0.29] | 10 studies · 916 participants | Very low |
Recurrent ischaemic or unknown stroke during treatment period Summary of findings table ‐ Anticoagulant vs control | OR 0.75 [0.65, 0.88] | 12 studies · 21665 participants | Moderate |
Symptomatic intracranial haemorrhage during treatment period Summary of findings table ‐ Anticoagulant vs control | OR 2.47 [1.9, 3.21] | 21 studies · 23221 participants | Moderate |
Symptomatic pulmonary embolism during treatment period Summary of findings table ‐ Anticoagulant vs control | OR 0.6 [0.44, 0.81] | 14 studies · 22544 participants | High |
Major extracranial haemorrhage during treatment period Summary of findings table ‐ Anticoagulant vs control | OR 2.99 [2.24, 3.99] | 18 studies · 22255 participants | Moderate |