What do systematic reviews say?

Zinc supplementation in pregnant women vs supplementation without zinc or placebo to reduce stunting

Zinc supplementation in pregnant women showed no clear difference in length (cm) at birth compared with supplementation without zinc or placebo to reduce stunting (moderate certainty).

• Nutritional interventions for preventing stunting in children (birth to 59 months) living in urban slums in low‐ and… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 1337 participants
  Moderate

Zinc supplementation in pregnant women vs supplementation without zinc or placebo to reduce stunting

• Nutritional interventions for preventing stunting in children (birth to 59 months) living in urban slums in low‐ and… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 237 participants
  Low

Zinc supplementation in pregnant women vs supplementation without zinc or placebo to reduce stunting

Zinc supplementation in pregnant women showed no clear difference in low birth weight (g) compared with supplementation without zinc or placebo to reduce stunting (moderate certainty).

• Nutritional interventions for preventing stunting in children (birth to 59 months) living in urban slums in low‐ and… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 1367 participants
  Moderate

Zinc vs no zinc supplementation

Zinc supplementation showed no clear difference in preterm birth (< 37 weeks) compared with no zinc (with or without placebo) (low certainty).

• Zinc supplementation for improving pregnancy and infant outcome 2021 · Cochrane Headline outcomes only
  RR 0.87 [0.74, 1.03]
  21 studies · 9851 participants
  Low

Zinc vs no zinc supplementation

Zinc supplementation showed no clear difference in stillbirth compared with no zinc (with or without placebo) (low certainty).

• Zinc supplementation for improving pregnancy and infant outcome 2021 · Cochrane Headline outcomes only
  RR 1.22 [0.8, 1.88]
  7 studies · 3295 participants
  Low

Zinc vs no zinc supplementation

It is very uncertain whether zinc supplementation changes neonatal death compared with no zinc (with or without placebo) (very low certainty).

• Zinc supplementation for improving pregnancy and infant outcome 2021 · Cochrane Headline outcomes only
  RR 2.44 [0.4, 14.83]
  3 studies · 1965 participants
  Very low

Zinc vs no zinc supplementation

Zinc supplementation showed no clear difference in perinatal death compared with no zinc (with or without placebo) (low certainty).

• Zinc supplementation for improving pregnancy and infant outcome 2021 · Cochrane Headline outcomes only
  RR 1.1 [0.81, 1.51]
  2 studies · 2489 participants
  Low

Zinc vs no zinc supplementation

• Zinc supplementation for improving pregnancy and infant outcome 2021 · Cochrane Headline outcomes only
  no estimate extracted
  22 studies · 7977 participants
  Low

Zinc vs no zinc supplementation

Zinc supplementation showed no clear difference in small‐for‐gestational age or IUGR compared with no zinc (with or without placebo) (moderate certainty).

• Zinc supplementation for improving pregnancy and infant outcome 2021 · Cochrane Headline outcomes only
  RR 1.02 [0.92, 1.12]
  9 studies · 5330 participants
  Moderate

Zinc vs no zinc supplementation

Zinc supplementation showed no clear difference in low Birthweight (< 2500 g) compared with no zinc (with or without placebo) (moderate certainty).

• Zinc supplementation for improving pregnancy and infant outcome 2021 · Cochrane Headline outcomes only
  RR 0.94 [0.79, 1.13]
  17 studies · 7399 participants
  Moderate