Findings

What do systematic reviews say?

9 questions · 9 findings · 1 reviews · Oral and maxillofacial surgery · All outcomes

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No studies found 3 · 33.3%GRADE not reported 5 · 55.6%Very low 1 · 11.1%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Zinc oxide and eugenol (ZOE) vs Alvogyl (old formulation)

Limitation of chewing or swallowing · Adults (>18 years) with established dry socket following permanent tooth extraction

The review found no eligible studies for this question.

1 finding from 1 review

Local interventions for the management of alveolar osteitis (dry socket) 2022 · Cochrane All outcomes
No studies reported this outcome
0 studies
No studies found

Zinc oxide and eugenol (ZOE) vs Alvogyl (old formulation)

Swelling (mean) · Adults (>18 years) with established dry socket following permanent tooth extraction

The review found no eligible studies for this question.

1 finding from 1 review

Local interventions for the management of alveolar osteitis (dry socket) 2022 · Cochrane All outcomes
No studies reported this outcome
0 studies
No studies found

Zinc oxide and eugenol (ZOE) vs Alvogyl (old formulation)

Fever · Adults (>18 years) with established dry socket following permanent tooth extraction

The review found no eligible studies for this question.

1 finding from 1 review

Local interventions for the management of alveolar osteitis (dry socket) 2022 · Cochrane All outcomes
No studies reported this outcome
0 studies
No studies found

Zinc oxide and eugenol (ZOE) vs Alvogyl (old formulation)

Success rate (radiographically‐assessed healing of cyst healing based on the Neer/Cole rating system) · Adults (>18 years) with established dry socket following permanent tooth extraction

1 finding from 1 review

Local interventions for the management of alveolar osteitis (dry socket) 2022 · Cochrane All outcomes
Healing: 2 studies (Faizel 2015; Supe 2018) used different healing outcomes and could not be combined; Alvogyl appeared to heal faster than zinc oxide eugenol. Supe 2018: delayed (non-healed after 10 days) 2/25 Alvogyl…
2 studies
GRADE not reported

Zinc oxide and eugenol (ZOE) vs Alvogyl (old formulation)

Pain (VAS 0-10) · Adults (>18 years) with established dry socket following permanent tooth extraction

It is very uncertain whether zinc oxide eugenol changes pain (VAS 0-10) compared with alvogyl (old formulation) (very low certainty).

1 finding from 1 review

Local interventions for the management of alveolar osteitis (dry socket) 2022 · Cochrane All outcomes
Day 7
MD 1.40 [1.04, 1.75]
2 studies · 80 participants
Very low

Alvogyl vs Zinc oxide and eugenol (ZOE)

Mean time to resolution of pain · Adults (>18 years) with established dry socket following permanent tooth extraction

Alvogyl led to lower time to complete resolution of pain (days) compared with zinc oxide eugenol; GRADE not reported.

1 finding from 1 review

Local interventions for the management of alveolar osteitis (dry socket) 2022 · Cochrane All outcomes
Complete resolution of pain
MD -2.17 [-2.37, -1.97]
1 study · 78 participants
GRADE not reported

Neocone vs Zinc oxide and eugenol (ZOE)

Time to initial pain relief (minutes) · Adults (>18 years) with established dry socket following permanent tooth extraction

Neocone led to lower time to initial pain relief (minutes) compared with zinc oxide eugenol; GRADE not reported.

1 finding from 1 review

Local interventions for the management of alveolar osteitis (dry socket) 2022 · Cochrane All outcomes
Initial pain relief
MD -7.77 [-8.86, -6.68]
1 study · 78 participants
GRADE not reported

Neocone vs Zinc oxide and eugenol (ZOE)

Mean time to resolution of pain · Adults (>18 years) with established dry socket following permanent tooth extraction

Neocone led to lower time to complete resolution of pain (days) compared with zinc oxide eugenol; GRADE not reported.

1 finding from 1 review

Local interventions for the management of alveolar osteitis (dry socket) 2022 · Cochrane All outcomes
Complete resolution of pain
MD -3.79 [-4.04, -3.54]
1 study · 78 participants
GRADE not reported

Alvogyl vs Zinc oxide and eugenol (ZOE)

Time to initial pain relief (minutes) · Adults (>18 years) with established dry socket following permanent tooth extraction

Alvogyl led to lower time to initial pain relief (minutes) compared with zinc oxide eugenol; GRADE not reported.

1 finding from 1 review

Local interventions for the management of alveolar osteitis (dry socket) 2022 · Cochrane All outcomes
Initial pain relief
MD -17.64 [-18.76, -16.52]
1 study · 78 participants
GRADE not reported