Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews · Dental caries

No studies found 0 · 0%GRADE not reported 3 · 60%Very low 1 · 20%Low 1 · 20%Moderate 0 · 0%High 0 · 0%

Caries increment (DFS) · adults

1 finding from 1 review

Xylitol‐containing products for preventing dental caries in children and adults 2015 · Cochrane All outcomes
33 months
PF 0.08 [-0.03, 0.20]
1 study · 669 participants
Low

Adverse effects (sores in the mouth, cramps, bloating, constipation, flatulence, loose stool or diarrhoea) · adults

1 finding from 1 review

Xylitol‐containing products for preventing dental caries in children and adults 2015 · Cochrane All outcomes
33 months
Patterns of adverse effects (sores in the mouth, cramps, bloating, constipation, flatulence, and loose stool or diarrhoea) were similar for both groups. Bader 2013.
1 study · 669 participants
GRADE not reported

Adverse effects · Children (permanent teeth; baseline 8 to 10 years)

1 finding from 1 review

Xylitol‐containing products for preventing dental caries in children and adults 2015 · Cochrane All outcomes
24 months (48-month follow-up)
There were no usable data presented for adverse effects. Lenkkeri 2012.
1 study
GRADE not reported

Caries increment, surface index D(M)FS · Children (permanent teeth; baseline 8 to 10 years)

1 finding from 1 review

Xylitol‐containing products for preventing dental caries in children and adults 2015 · Cochrane All outcomes
24 months (48-month follow-up)
PF -0.10 [-0.59, 0.39]
1 study · 200 participants
Very low

Number of children with a caries increment · Children (permanent teeth; baseline 8 to 10 years)

Xylitol lozenges (4.7 g/day) showed no clear difference in number of children with a caries increment compared with no treatment; GRADE not reported.

1 finding from 1 review

Xylitol‐containing products for preventing dental caries in children and adults 2015 · Cochrane All outcomes
24 months (48-month follow-up)
RR 1.02 [0.83, 1.26]
1 study · 200 participants
GRADE not reported