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Evidence found and GRADE certainty

66 questions · 66 findings · 4 reviews · Effective Practice and Organisation of Care

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No studies found 12 · 18.2%GRADE not reported 3 · 4.5%Very low 11 · 16.7%Low 29 · 43.9%Moderate 5 · 7.6%High 6 · 9.1%

Primary‐level worker‐led collaborative care vs usual care

Prevalence of CMD ‐ intermediate term (1 to 6 months post intervention) Diagnosis defined by presence of ICD‐10 diagnosis on CIS‐Rg; prevalence defined by [Total number ‐ number recovered (recovery defined by HDRS < 8)]c (RR < 1 denotes lower prev... · adults with common mental disorders

Primary‐level worker‐led collaborative care showed no clear difference in prevalence of CMD ‐ intermediate term (1 to 6 months post… compared with usual care (low certainty).

1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Recovery from CMD ‐ intermediate term (1 to 6 months post intervention) Recovery defined by GDS ≤ 11a; HDRS < 7b; HDRS < 8c; PHQ‐9 < 6d; PHQ‐9 < 5 or 50% reduction from baselinee (RR > 1 denotes greater likelihood of recovery) · adults with common mental disorders

Lay health worker‐led psychological interventions may leads to higher recovery from CMDs ‐ intermediate term (1 to 6 months post… compared with usual care (low certainty).

1 finding from 1 review

Community professional‐led interventions vs no care

Recovery from probable PTSD in children (< 1 month post intervention) Defined by number of participants whose CRIES‐13 score was above cutoff for diagnosis of PTSD at baseline ‐ number of participants whose CRIES‐13 score was above cutoff for the ... · children/adolescents with post‐traumatic stress and related depressive/anxiety symptoms

It is very uncertain whether community professional‐led interventions changes recovery from probable PTSD in children (< 1 month post… compared with no care (very low certainty).

1 finding from 1 review

Lay health worker‐led psychosocial interventions vs enhanced usual care

Depression recovery ‐ intermediate term (1 to 6 months post intervention) · women with perinatal depression

Lay health worker‐led psychosocial interventions may leads to higher recovery from depression ‐ intermediate term (1 to 6 months post… compared with enhanced usual care (low certainty).

1 finding from 1 review

Lay health worker‐led interventions for adult patients with harmful or hazardous alcohol or substance use vs enhanced usual care

Clinical recovery ‐ harmful or hazardous alcohol use (1 to 6 months post intervention) · adult patients with harmful or hazardous alcohol or substance use

Lay health worker‐led interventions for adult patients with harmful… showed no clear difference in clinical recovery ‐ harmful or hazardous alcohol use (1 to 6 months… compared with enhanced usual care (low certainty).

1 finding from 1 review

Primary health professional‐ and community professional‐led interventions vs enhanced usual care

Clinical recovery ‐ harmful or hazardous alcohol use (1 to 6 months post intervention) · adult patients with harmful or hazardous alcohol or substance use

Primary health professional‐ and community professional‐led… showed no clear difference in clinical recovery ‐ harmful or hazardous alcohol use (1 to 6 months… compared with enhanced usual care (moderate certainty).

1 finding from 1 review

Lay health worker‐ vs enhanced usual care

Clinical recovery ‐ harmful or dependent alcohol use (1 to 6 months post intervention) Defined by AUDIT score < 8 (RR > 1 denotes higher likelihood of recovery) · adult patients with alcohol dependence

It is very uncertain whether lay health worker‐led interventions changes clinical recovery ‐ harmful or dependent alcohol use (1 to 6 months… compared with enhanced usual care (very low certainty).

1 finding from 1 review

Lay health worker‐ vs specialist‐led care

Clinical recovery from severe mental disorder (immediately post intervention) Defined by BPRS decreased by ≥ 80% (RR > 1 denotes greater likelihood of recovery) · people with severe mental disorders

The review found no eligible studies for this question.

1 finding from 1 review

Primary‐level worker‐led collaborative care vs usual care

Recovery from CMD ‐ intermediate term (1 to 6 months post intervention) Recovery defined by GDS ≤ 11a; HDRS < 7b; HDRS < 8c; PHQ‐9 < 6d; PHQ‐9 < 5 or 50% reduction from baselinee (RR > 1 denotes greater likelihood of recovery) · adults with common mental disorders

Primary‐level worker‐led collaborative care may leads to higher recovery from CMD ‐ intermediate term (1 to 6 months post… compared with usual care (low certainty).

1 finding from 1 review

Primary health professional‐led or collaborative care vs specialist‐led care

Clinical recovery from severe mental disorder (immediately post intervention) Defined by BPRS decreased by ≥ 80% (RR > 1 denotes greater likelihood of recovery) · people with severe mental disorders

It is very uncertain whether primary health professional‐led or collaborative care changes clinical recovery from severe mental disorder (immediately post… compared with specialist‐led care (very low certainty).

1 finding from 1 review