Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 50%Moderate 2 · 50%High 0 · 0%

Remission · patients with induction of remission in ulcerative colitis

Type I Interferons showed no clear difference in remission compared with placebo (moderate certainty).

1 finding from 1 review

Type I interferons for induction of remission in ulcerative colitis 2015 · Cochrane Headline outcomes only
RR 1.16 [0.84, 1.58]
4 studies · 362 participants
Moderate

Clinical improvement · patients with induction of remission in ulcerative colitis

Type I Interferons showed no clear difference in clinical improvement compared with placebo (moderate certainty).

1 finding from 1 review

Type I interferons for induction of remission in ulcerative colitis 2015 · Cochrane Headline outcomes only
RR 1.16 [0.96, 1.4]
4 studies · 425 participants
Moderate

Serious adverse events · patients with induction of remission in ulcerative colitis

Type I Interferons showed no clear difference in serious adverse events compared with placebo (low certainty).

1 finding from 1 review

Type I interferons for induction of remission in ulcerative colitis 2015 · Cochrane Headline outcomes only
RR 0.74 [0.13, 4.14]
4 studies · 468 participants
Low

Withdrawals due to adverse events · patients with induction of remission in ulcerative colitis

Type I Interferons may leads to higher withdrawals due to adverse events compared with placebo (low certainty).

1 finding from 1 review

Type I interferons for induction of remission in ulcerative colitis 2015 · Cochrane Headline outcomes only
RR 3.16 [1.06, 9.4]
4 studies · 394 participants
Low