Findings

What do systematic reviews say?

21 questions · 21 findings · 1 reviews

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No studies found 6 · 28.6%GRADE not reported 0 · 0%Very low 3 · 14.3%Low 10 · 47.6%Moderate 2 · 9.5%High 0 · 0%

Closest answers

The findings closest to your search, judged one by one by TypeSafe's Jev model.

Direct match · question page
- Transabdominal chorionic villus sampling vs second trimester amniocentesis · Spontaneous miscarriage
  Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
  RR 0.77 [0.49, 1.21]
  1 study · 2069 participants
  Low
Direct match · question page
- Transabdominal chorionic villus sampling vs second trimester amniocentesis · All known pregnancy loss (including termination of pregnancy)
  Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
  RR 0.9 [0.66, 1.23]
  1 study · 2234 participants
  Low
Direct match · question page
- Transabdominal chorionic villus sampling vs second trimester amniocentesis · Perinatal deaths (stillbirths and neonatal deaths in the first week of life)
  Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
  RR 1.18 [0.4, 3.51]
  1 study · 2069 participants
  Low
Direct match · question page
- Transabdominal chorionic villus sampling vs second trimester amniocentesis · Delivery before 33 weeks
  Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
Direct match · question page
- Transabdominal chorionic villus sampling vs second trimester amniocentesis · Sampling failure
  Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Transabdominal chorionic villus sampling vs second trimester amniocentesis

Sampling failure · prenatal diagnosis

The review found no eligible studies for this question.

1 finding from 1 review

Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Transabdominal chorionic villus sampling vs second trimester amniocentesis

All known pregnancy loss (including termination of pregnancy) · prenatal diagnosis

Transabdominal chorionic villus sampling showed no clear difference in all known pregnancy loss (including termination of pregnancy) compared with second trimester amniocentesis (low certainty).

1 finding from 1 review

Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
RR 0.9 [0.66, 1.23]
1 study · 2234 participants
Low

Transabdominal chorionic villus sampling vs second trimester amniocentesis

Miscarriage · prenatal diagnosis

Transabdominal chorionic villus sampling showed no clear difference in spontaneous miscarriage compared with second trimester amniocentesis (low certainty).

1 finding from 1 review

Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
RR 0.77 [0.49, 1.21]
1 study · 2069 participants
Low

Transabdominal chorionic villus sampling vs second trimester amniocentesis

Laboratory failure · prenatal diagnosis

The review found no eligible studies for this question.

1 finding from 1 review

Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Transabdominal chorionic villus sampling vs second trimester amniocentesis

Known false negative after birth · prenatal diagnosis

The review found no eligible studies for this question.

1 finding from 1 review

Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Transabdominal chorionic villus sampling vs second trimester amniocentesis

Delivery before 33 weeks · prenatal diagnosis

The review found no eligible studies for this question.

1 finding from 1 review

Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Transabdominal chorionic villus sampling vs second trimester amniocentesis

Perinatal death (stillbirth + death in first week of life) · prenatal diagnosis

Transabdominal chorionic villus sampling showed no clear difference in perinatal deaths (stillbirths and neonatal deaths in the first week… compared with second trimester amniocentesis (low certainty).

1 finding from 1 review

Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
RR 1.18 [0.4, 3.51]
1 study · 2069 participants
Low

Transcervical vs transabdominal chorionic villus sampling

Sampling failure · prenatal diagnosis

Transcervical probably leads to higher sampling failure compared with transabdominal chorionic villus sampling (moderate certainty).

1 finding from 1 review

Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
RR 1.79 [1.13, 2.82]
4 studies · 5231 participants
Moderate

Early amniocentesis vs transabdominal chorionic villus sampling

Sampling failure · prenatal diagnosis

Early amniocentesis showed no clear difference in sampling failure compared with transabdominal chorionic villus sampling (low certainty).

1 finding from 1 review

Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
RR 0.58 [0.24, 1.38]
4 studies · 5566 participants
Low

Transcervical vs transabdominal chorionic villus sampling

All known pregnancy loss (including termination of pregnancy) · prenatal diagnosis

It is very uncertain whether transcervical changes all known pregnancy loss (including termination of pregnancy) compared with transabdominal chorionic villus sampling (very low certainty).

1 finding from 1 review

Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
RR 1.16 [0.81, 1.65]
5 studies · 7978 participants
Very low

Transcervical vs transabdominal chorionic villus sampling

Miscarriage · prenatal diagnosis

It is very uncertain whether transcervical changes spontaneous miscarriage compared with transabdominal chorionic villus sampling (very low certainty).

1 finding from 1 review

Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
RR 1.68 [0.79, 3.58]
4 studies · 3384 participants
Very low

Transcervical vs transabdominal chorionic villus sampling

Laboratory failure · prenatal diagnosis

Transcervical showed no clear difference in laboratory failure compared with transabdominal chorionic villus sampling (low certainty).

1 finding from 1 review

Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
RR 2.23 [0.69, 7.22]
1 study · 1194 participants
Low

Transcervical vs transabdominal chorionic villus sampling

Known false negative after birth · prenatal diagnosis

The review found no eligible studies for this question.

1 finding from 1 review

Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Transcervical vs transabdominal chorionic villus sampling

Delivery before 33 weeks · prenatal diagnosis

The review found no eligible studies for this question.

1 finding from 1 review

Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Transcervical vs transabdominal chorionic villus sampling

Anomalies (all recorded) · prenatal diagnosis

Transcervical showed no clear difference in anomalies (all recorded) compared with transabdominal chorionic villus sampling (low certainty).

1 finding from 1 review

Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
RR 0.68 [0.41, 1.12]
2 studies · 3622 participants
Low

Early amniocentesis vs transabdominal chorionic villus sampling

All known pregnancy loss (including termination of pregnancy) · prenatal diagnosis

Early amniocentesis showed no clear difference in all known pregnancy loss (including termination of pregnancy) compared with transabdominal chorionic villus sampling (low certainty).

1 finding from 1 review

Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
RR 1.15 [0.86, 1.54]
4 studies · 5491 participants
Low

Early amniocentesis vs transabdominal chorionic villus sampling

Miscarriage · prenatal diagnosis

Early amniocentesis probably leads to higher spontaneous miscarriage compared with transabdominal chorionic villus sampling (moderate certainty).

1 finding from 1 review

Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
RR 1.73 [1.15, 2.6]
4 studies · 5491 participants
Moderate

Early amniocentesis vs transabdominal chorionic villus sampling

Laboratory failure · prenatal diagnosis

Early amniocentesis showed no clear difference in laboratory failure compared with transabdominal chorionic villus sampling (low certainty).

1 finding from 1 review

Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
RR 0.74 [0.34, 1.63]
4 studies · 5566 participants
Low

Early amniocentesis vs transabdominal chorionic villus sampling

Known false negative after birth · prenatal diagnosis

1 finding from 1 review

Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 555 participants
Low

Early amniocentesis vs transabdominal chorionic villus sampling

Delivery before 33 weeks · prenatal diagnosis

Early amniocentesis showed no clear difference in delivery before 33 weeks compared with transabdominal chorionic villus sampling (low certainty).

1 finding from 1 review

Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
RR 0.5 [0.09, 2.73]
1 study · 1121 participants
Low