Findings

What do systematic reviews say?

7 questions · 7 findings · 2 reviews

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No studies found 4 · 57.1%GRADE not reported 2 · 28.6%Very low 1 · 14.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Tinidazole vs placebo

Clinical remission · Patients with ileal pouch‐anal anastomosis

The review found no eligible studies for this question.

1 finding from 1 review

Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Tinidazole vs placebo

Clinical improvement · Patients with ileal pouch‐anal anastomosis

The review found no eligible studies for this question.

1 finding from 1 review

Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Tinidazole vs placebo

Maintenance of clinical remission · Patients with ileal pouch‐anal anastomosis

The review found no eligible studies for this question.

1 finding from 1 review

Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Tinidazole vs placebo

No episodes of acute pouchitis · Patients with ileal pouch‐anal anastomosis

It is very uncertain whether tinidazole changes no episodes of acute pouchitis compared with placebo (very low certainty).

1 finding from 1 review

Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis 2019 · Cochrane Headline outcomes only
RR 1.38 [0.83, 2.31]
1 study · 38 participants
Very low

Tinidazole vs placebo

Adverse events · Patients with ileal pouch‐anal anastomosis

The review found no eligible studies for this question.

1 finding from 1 review

Treatment and prevention of pouchitis after ileal pouch‐anal anastomosis for chronic ulcerative colitis 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Rofecoxib (oral, 50 mg on first day then 25 to 50 mg per day for 4 days) vs Tinidazole (1 g per day for 3 days)

Total effective rate at 4 days · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…

Rofecoxib (oral, 50 mg on first day then 25 to 50 mg per day for 4… showed no clear difference in total effective rate at 4 days compared with tinidazole (1 g per day for 3 days); GRADE not reported.

1 finding from 1 review

Systemic interventions for recurrent aphthous stomatitis (mouth ulcers) 2012 · Cochrane All outcomes
4 days
RR 1.17 [0.95, 1.43]
1 study · 60 participants
GRADE not reported

Rofecoxib (oral, 50 mg on first day then 25 to 50 mg per day for 4 days) vs Tinidazole (1 g per day for 3 days)

Adverse effects · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…

1 finding from 1 review

Systemic interventions for recurrent aphthous stomatitis (mouth ulcers) 2012 · Cochrane All outcomes
4 days
No adverse effects reported in translation.
1 study · 60 participants
GRADE not reported