Findings

What do systematic reviews say?

3 questions · 3 findings · 2 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 33.3%Moderate 0 · 0%High 2 · 66.7%

Completion of treatment Objective · patients with the management of opioid withdrawal

Tapered methadone showed no clear difference in completion of treatment Objective compared with any other treatment (high certainty).

1 finding from 1 review

Methadone at tapered doses for the management of opioid withdrawal 2013 · Cochrane Headline outcomes only
RR 1.08 [0.97, 1.21]
16 studies · 1381 participants
High

Abstinents at · patients with the management of opioid withdrawal

Tapered methadone showed no clear difference in number of participants abstinent at compared with any other treatment (high certainty).

1 finding from 1 review

Methadone at tapered doses for the management of opioid withdrawal 2013 · Cochrane Headline outcomes only
RR 0.98 [0.7, 1.37]
3 studies · 386 participants
High

Retained in naltrexone maintenance treatment or abstinent at 12 weeks ‐ Tapered methadone comparison · patients with opioid withdrawal

The intervention showed no clear difference in retained in naltrexone maintenance treatment or abstinent at 12… (low certainty).

1 finding from 1 review

Opioid antagonists under heavy sedation or anaesthesia for opioid withdrawal 2010 · Cochrane Headline outcomes only
RR 2 [0.9, 4.45]
1 study · 30 participants
Low