TCAs with predominantly SRI actions vs other TCAs
Treatment responseaPhysician‐rated Clinical Progress Scale · adults with trichotillomania
1 finding from 1 review
- no estimate extracted1 study · 26 participantsLow
Findings
What do systematic reviews say?
6 questions · 6 findings · 1 reviews
No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 50%Low 3 · 50%Moderate 0 · 0%High 0 · 0%
TCAs with predominantly SRI actions vs other TCAs
Reduction of TTM symptom severityNIMH Trichotillomania Severity Scale (NIMH‐TSS) · adults with trichotillomania
1 finding from 1 review
- no estimate extracted1 study · 26 participantsLow
TCAs with predominantly SRI actions vs other TCAs
Withdrawals due to adverse events · adults with trichotillomania
1 finding from 1 review
- no estimate extracted1 study · 26 participantsLow
TCAs with predominantly SRI actions vs placebo
Clinical Global Impressions scale change item (CGI‐I): no. of responders (long term) Post‐treatment: 1‐4 months · adults with trichotillomania
It is very uncertain whether TCAs with predominantly SRI actions changes treatment responseaClinical Global Impressions ‐ Improvement Scale… compared with placebo (very low certainty).
1 finding from 1 review
- RR 5.73 [0.36, 90.83]1 study · 16 participantsVery low
TCAs with predominantly SRI actions vs placebo
Reduction of TTM symptom severityNIMH Trichotillomania Severity Scale (NIMH‐TSS) · adults with trichotillomania
1 finding from 1 review
- no estimate extracted1 study · 16 participantsVery low
TCAs with predominantly SRI actions vs placebo
Dropouts due to adverse events · adults with trichotillomania
It is very uncertain whether TCAs with predominantly SRI actions changes tolerability of treatment ‐ dropouts due to adverse eventsdDropout… compared with placebo (very low certainty).
1 finding from 1 review
- RR 4.45 [0.27, 73.81]1 study · 16 participantsVery low