Healing of MRONJ · People with established (manifest) MRONJ
It is very uncertain whether autofluorescence-guided bone surgery changes healing of MRONJ compared with conventional bone surgery (very low certainty).
1 finding from 1 review
Healing of MRONJ (mucosal integrity) · People with MRONJ referred for surgical treatment
It is very uncertain whether autofluorescence-guided bone surgery changes healing of MRONJ (mucosal integrity) compared with tetracycline fluorescence-guided bone surgery (very low certainty).
1 finding from 1 review
Healing of MRONJ · People with established (manifest) MRONJ
It is very uncertain whether platelet-rich fibrin after bone surgery changes healing of MRONJ (mucosal integrity and absence of infection) compared with bone surgery alone (very low certainty).
1 finding from 1 review
Healing of MRONJ (mucosal integrity, absence of infection, and no re-intervention) · People with established (manifest) MRONJ
It is very uncertain whether platelet-rich fibrin after bone surgery changes healing of MRONJ (mucosal integrity, absence of infection, and no… compared with bone surgery alone (very low certainty).
1 finding from 1 review
Healing of osteonecrosis - improvement ('healed' or 'improved' vs 'unchanged' or 'worse') · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
Hyperbaric oxygen therapy plus standard care (surgery, antibiotics,… showed no clear difference in healing of osteonecrosis - improvement ('healed' or 'improved' vs… compared with standard care alone (surgery, antibiotics, oral rinse); GRADE not reported.
5 findings from 1 review
RR 1.75 [0.51, 5.98]
1 study · 18 participants
GRADE not reported
RR 1.78 [0.97, 3.28]
1 study · 46 participants
GRADE not reported
RR 1.94 [1.01, 3.74]
1 study · 45 participants
Very low
Show 2 more findings
Healing of osteonecrosis - healed ('healed' vs 'improved', 'unchanged' or 'worse') · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
Hyperbaric oxygen therapy plus standard care (surgery, antibiotics,… showed no clear difference in healing of osteonecrosis - healed ('healed' vs 'improved',… compared with standard care alone (surgery, antibiotics, oral rinse); GRADE not reported.
5 findings from 1 review
RR 1.56 [0.77, 3.18]
1 study · 46 participants
GRADE not reported
RR 1.00 [0.25, 4.00]
1 study · 18 participants
GRADE not reported
RR 0.95 [0.44, 2.04]
1 study · 40 participants
GRADE not reported
Show 2 more findings
Pain · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
1 finding from 1 review
Adverse effects · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Quality of life · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
1 finding from 1 review
Time to feeding after surgery · Children up to 13 years of age, undergoing cleft lip repair surgery
The review found no eligible studies for this question.
1 finding from 1 review
Time to feeding after surgery · Children up to 13 years of age, undergoing cleft lip repair surgery
Perioperative infraorbital nerve block may leads to lower time to feeding after surgery (in minutes) compared with intravenous analgesia (low certainty).
1 finding from 1 review
Time to feeding after surgery · Children up to 13 years of age, undergoing cleft lip repair surgery
The review found no eligible studies for this question.
1 finding from 1 review
Clinical evaluations 12 months after surgery (6 pooled clinical signs) · Adults (older than 18 years) with a temporomandibular disorder (synovitis, disc displacement with or without reduction, myofascial…
Arthroscopy showed no clear difference in clinical evaluations 12 months after surgery (6 pooled clinical signs) compared with open surgery; GRADE not reported.
1 finding from 1 review
Adverse effect: failure of muscle fusion in the region of the cleft after surgery · Children or adolescents aged 3 years or older with velopharyngeal insufficiency (VPI) associated with non-syndromic submucous cleft palate
1 finding from 1 review
Weight (kg) · Infants up to 6 months (from term) born with cleft lip, cleft palate or cleft lip and palate (Pierre Robin sequence or other syndromes…
Breastfeeding (post cleft-lip surgery) led to higher weight (kg) compared with spoon-feeding; GRADE not reported.
1 finding from 1 review
Length of hospital stay · Infants up to 6 months (from term) born with cleft lip, cleft palate or cleft lip and palate (Pierre Robin sequence or other syndromes…
1 finding from 1 review
Adverse events (wound dehiscence; lip scar hypertrophy) · Infants up to 6 months (from term) born with cleft lip, cleft palate or cleft lip and palate (Pierre Robin sequence or other syndromes…
1 finding from 1 review
Adverse events: one wound dehiscence and one hypertrophy of the lip scar, both in spoon-fed infants (Darzi 1996).
1 study · 40 participants
GRADE not reported
Cost of hospitalisation · Infants up to 6 months (from term) born with cleft lip, cleft palate or cleft lip and palate (Pierre Robin sequence or other syndromes…
1 finding from 1 review
Complications and side effects · People treated with oral bisphosphonates undergoing dental extractions (at risk of MRONJ)
1 finding from 1 review
MRONJ (incidence proportion) · People treated with oral bisphosphonates undergoing dental extractions (at risk of MRONJ)
1 finding from 1 review
In both study arms, no case of postoperative MRONJ was observed (700 participants; 1 RCT); effect not estimable.
1 study · 700 participants
GRADE not reported