Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

128 questions · 192 findings · 29 reviews · All outcomes

No studies found 16 · 8.3%GRADE not reported 111 · 57.8%Very low 12 · 6.3%Low 26 · 13.5%Moderate 24 · 12.5%High 3 · 1.6%

Turned (smoother) implant surfaces vs Roughened implant surfaces

Early implant failure · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year

Turned (smoother) implant surfaces showed no clear difference in early implant failure compared with roughened implant surfaces (low certainty).

1 finding from 1 review

Turned (smoother) implant surfaces vs Roughened implant surfaces

Peri-implantitis · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year

Turned (smoother) implant surfaces may leads to lower peri-implantitis compared with roughened implant surfaces (low certainty).

1 finding from 1 review

Astra cylindrical turned surface implants vs Astra cylindrical TiO2-blasted surface implants

Implant failure · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year
1 finding from 1 review

Implant surface smoothening added to systemic antibiotics + resective surgery + local antibiotics vs No implant surface smoothening (same surgical protocol)

Implant failure · People with at least one dental implant affected by perimplantitis

Implant surface smoothening added to systemic antibiotics +… showed no clear difference in implant failure compared with no implant surface smoothening (same surgical protocol); GRADE not reported.

1 finding from 1 review

Radiographic imaging methods (any: analogue radiographs, digital radiographs, or CBCT) vs Reference standard (histology, excavation, or enhanced visual examination)

Diagnostic accuracy on surfaces with pit and fissure sealants · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…

The review found no eligible studies for this question.

1 finding from 1 review
  • Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomes
    Up to 3 months between index test and reference standard (in vivo studies) · Pit and fissure sealants
    Pre-specified heterogeneity investigation of surfaces with pit and fissure sealants: no study reported the inclusion of sealants that would allow evaluation of early caries lesions.
    0 studies
    No studies found

Er:YAG laser surface debridement before bone augmentation vs Plastic curettes plus saline solution before bone augmentation

Change in probing attachment level (PAL) · People with at least one dental implant affected by perimplantitis

Er:YAG laser surface debridement before bone augmentation showed no clear difference in change in probing attachment level (PAL gain) compared with plastic curettes plus saline solution before bone augmentation; GRADE not reported.

1 finding from 1 review

Er:YAG laser surface debridement before bone augmentation vs Plastic curettes plus saline solution before bone augmentation

Complications and side effects · People with at least one dental implant affected by perimplantitis

Er:YAG laser surface debridement before bone augmentation led to lower complications and side effects compared with plastic curettes plus saline solution before bone augmentation; GRADE not reported.

1 finding from 1 review

Er:YAG laser surface debridement before bone augmentation vs Plastic curettes plus saline solution before bone augmentation

Change in probing pocket depth (PPD) · People with at least one dental implant affected by perimplantitis

Er:YAG laser surface debridement before bone augmentation showed no clear difference in change in probing pocket depth (PPD reduction) compared with plastic curettes plus saline solution before bone augmentation; GRADE not reported.

1 finding from 1 review

Er:YAG laser surface debridement before bone augmentation vs Plastic curettes plus saline solution before bone augmentation

Change in soft tissue recession (REC) · People with at least one dental implant affected by perimplantitis

Er:YAG laser surface debridement before bone augmentation showed no clear difference in change in soft tissue recession (REC) compared with plastic curettes plus saline solution before bone augmentation; GRADE not reported.

1 finding from 1 review

Advice about a healthy diet (including breastfeeding promotion and sugar avoidance) and feeding practices (e.g. relating to bottle-feeding and sleep) for infants and young children vs usual care

dmfs index score (decayed, missing, filled primary surfaces; range 0-80) · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes, children up to 6 years…

Advice about a healthy diet (including breastfeeding promotion and… showed no clear difference in dmfs index score (decayed, missing, filled primary surfaces; range… compared with standard care (low certainty).

1 finding from 1 review

Visual or visual-tactile classification systems (any system: ICDAS, ERK, Nyvad, Downer, Lussi, UniViSS, or unspecified) vs Reference standard (histology, excavation, radiographs/microCT, or tooth separation)

Diagnostic accuracy on surfaces with pit and fissure sealants · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…

The review found no eligible studies for this question.

1 finding from 1 review

Clinical examination with 24-month recall vs Clinical examination with 6-month recall

Dental caries · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)

Clinical examination with 24-month recall showed no clear difference in dental caries: number of tooth surfaces with any caries (ICDAS 1-6) compared with clinical examination with 6-month recall (moderate certainty).

1 finding from 1 review

Resin-based fissure sealant (visible-light-polymerized) vs Fluoride varnish

Incidence of dentinal carious lesion on treated occlusal surfaces of molars or premolars (yes/no) · Children and adolescents (general population, aged under 20 years)

It is very uncertain whether resin-based fissure sealant (visible-light-polymerized) changes incidence of dentinal carious lesion on treated occlusal surfaces of… compared with fluoride varnish (very low certainty).

2 findings from 1 review

Resin-modified glass ionomer fissure sealant plus oral health education vs Fluoride varnish plus oral health education

Change in DMF increment on occlusal surfaces of first permanent molars · Children and adolescents (general population, aged under 20 years)

Resin-modified glass ionomer fissure sealant plus oral health… showed no clear difference in change in DMF increment on occlusal surfaces of first permanent molars compared with fluoride varnish plus oral health education; GRADE not reported.

2 findings from 1 review

Clinical examination with risk-based recall vs Clinical examination with 6-month recall

Dental caries · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)

Clinical examination with risk-based recall showed no clear difference in dental caries: number of tooth surfaces with any caries (ICDAS 1-6) compared with clinical examination with 6-month recall (high certainty).

1 finding from 1 review

Resin-based fissure sealant vs Fluoride varnish

Change in DMFS (decayed, missing and filled permanent surfaces) increment · Children and adolescents (general population, aged under 20 years)

Resin-based fissure sealant led to lower change in DMFS (decayed, missing and filled permanent surfaces)… compared with fluoride varnish; GRADE not reported.

1 finding from 1 review

All fluorescence-based devices (red, blue, and green fluorescence combined) vs Reference standard (histology, excavation, or enhanced visual examination)

Diagnostic odds ratio (DOR) by subgroup: Smooth or secondary-caries surfaces (detection of early enamel caries, D1 threshold) · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
1 finding from 1 review

Clinical examination with risk-based recall vs Clinical examination with 24-month recall

Dental caries · Dentate adults (aged 18 years and older) receiving dental check-ups in UK general dental practices (regular attenders)

Clinical examination with risk-based recall showed no clear difference in dental caries: number of tooth surfaces with any caries (ICDAS 1-6) compared with clinical examination with 24-month recall (moderate certainty).

1 finding from 1 review