Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

33 questions · 34 findings · 4 reviews

No studies found 12 · 35.3%GRADE not reported 1 · 2.9%Very low 6 · 17.6%Low 4 · 11.8%Moderate 10 · 29.4%High 1 · 2.9%

Summary of findings TIVA vs inhalational maintenance of anaesthesia

Postoperative delirium (One study used DRS, three studies used CAM and in one study diagnostic tool was not reported) Time points were up to 4 days postoperatively

It is very uncertain whether summary of findings TIVA changes postoperative delirium (One study used DRS, three studies used CAM… compared with inhalational maintenance of anaesthesia (very low certainty).

1 finding from 1 review

Summary of findings TIVA vs inhalational maintenance of anaesthesia

Postoperative cognitive dysfunction (9 studies used MMSE, and 2 of these studies used additional diagnostic tools; 1 study used Trail Making Test and additional diagnostic tools; 3 studies did not report diagnostic tools) Time points were up to 30...

Summary of findings TIVA may leads to lower postoperative cognitive dysfunction (9 studies used MMSE, and 2 of… compared with inhalational maintenance of anaesthesia (low certainty).

1 finding from 1 review

Summary of findings for conjunctival autograft vs amniotic membrane transplant

Recurrence of pterygium · people with primary or recurrent pterygium

It is very uncertain whether summary of findings for conjunctival autograft changes recurrence of pterygium compared with amniotic membrane transplant (very low certainty).

2 findings from 1 review

Summary of findings table ‐ Recombinant activated factor VII vs placebo/open control

Death or dependence (mRS 4 to 6) at day 90 · adults with acute spontaneous intracerebral haemorrhage

Summary of findings table ‐ Recombinant activated factor VII showed no clear difference in death or dependence (mRS 4–6) compared with placebo/open control (low certainty).

1 finding from 1 review

Summary of findings table ‐ Recombinant activated factor VII vs placebo/open control

Intracerebral haemorrhage expansion by 24 hours · adults with acute spontaneous intracerebral haemorrhage

Summary of findings table ‐ Recombinant activated factor VII showed no clear difference in intracerebral haemorrhage expansion by 24 hours compared with placebo/open control (low certainty).

1 finding from 1 review

Summary of findings table ‐ Recombinant activated factor VII vs placebo/open control

All serious adverse events · adults with acute spontaneous intracerebral haemorrhage

It is very uncertain whether summary of findings table ‐ Recombinant activated factor VII changes all serious adverse events compared with placebo/open control (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Recombinant activated factor VII vs placebo/open control

Death from any cause · adults with acute spontaneous intracerebral haemorrhage

Summary of findings table ‐ Recombinant activated factor VII showed no clear difference in death from any cause compared with placebo/open control (moderate certainty).

1 finding from 1 review